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1N02
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Solution Structure of a Circular-Permuted Variant of the Potent HIV-inactivating Protein Cyanovirin-N
分子名称: Cyanovirin-N
著者Barrientos, L.G, Gronenborn, A.M.
登録日2002-10-10
公開日2002-12-18
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Solution Structure of a Circular-Permuted Variant of the Potent HIV-inactivating Protein Cyanovirin-N: Structural Basis for Protein Stability and Oligosaccharide Interaction
J.Mol.Biol., 325, 2003
6X7H
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Cyanovirin-N Mutation I34Y with Dimannose bound
分子名称: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Fromme, R, Sharma, P, Ghirlanda, G.
登録日2020-05-30
公開日2021-06-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations.
Elife, 11, 2022
5K79
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Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog
分子名称: 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER
著者Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M.
登録日2016-05-25
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Glycan Binding of a New Cyanovirin-N Homolog.
J.Biol.Chem., 291, 2016
3S3Z
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Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L10
分子名称: SODIUM ION, Tandem Cyanovirin-N Dimer CVN2L10
著者Keeffe, J.R, Bjorkman, P.J, Mayo, S.L.
登録日2011-05-18
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
3S3Y
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Crystal Structure an Tandem Cyanovirin-N Dimer, CVN2L0
分子名称: SODIUM ION, TANDEM CYANOVIRIN-N DIMER CVN2L0
著者Keeffe, J.R, Bjorkman, P.J, Mayo, S.L.
登録日2011-05-18
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Proc.Natl.Acad.Sci.USA, 108, 2011
3CZZ
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Crystal structure of Cyanovirin-N domain B mutant
分子名称: Cyanovirin-N
著者Matei, E, Furey, W, Gronenborn, A.M.
登録日2008-04-30
公開日2008-08-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping.
Structure, 16, 2008
3EZM
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CYANOVIRIN-N
分子名称: PROTEIN (CYANOVIRIN-N)
著者Yang, F, Wlodawer, A.
登録日1998-12-15
公開日1998-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping.
J.Mol.Biol., 288, 1999
2Y1S
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Microvirin lectin
分子名称: Mannan-binding lectin
著者Bewley, C.A, Hussan, S.
登録日2010-12-10
公開日2011-04-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity.
J. Biol. Chem., 286, 2011
2YHH
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Microvirin:mannobiose complex
分子名称: MANNAN-BINDING LECTIN, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Hussan, S, Bewley, C.A, Clore, G.M, Gustchina, E, Ghirlando, R.
登録日2011-05-02
公開日2011-06-15
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Solution Structure of the Monovalent Lectin Microvirin in Complex with Man(Alpha)(1-2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity.
J.Biol.Chem., 286, 2011
2Z21
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Crystal Structure of a five site mutated Cyanovirin-N
分子名称: Cyanovirin-N
著者Fromme, R, Katilene, Z, Fromme, P, Ghirlanda, G.
登録日2007-05-17
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity.
Biochemistry, 46, 2007
2PYS
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Crystal Structure of a Five Site Mutated Cyanovirin-N with a Mannose Dimer Bound at 1.8 A Resolution
分子名称: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Fromme, R, Katilene, Z, Fromme, P, Ghirlanda, G.
登録日2007-05-16
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Monovalent Mutant of Cyanovirin-N Provides Insight into the Role of Multiple Interactions with gp120 for Antiviral Activity.
Biochemistry, 46, 2007
2RDK
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Five site mutated Cyanovirin-N with Mannose dimer bound
分子名称: Cyanovirin-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Fromme, R, Katiliene, Z, Fromme, P, Ghirlanda, G.
登録日2007-09-24
公開日2008-05-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution.
Protein Sci., 17, 2008
2RP3
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Solution Structure of Cyanovirin-N Domain B Mutant
分子名称: Cyanovirin-N
著者Matei, E, Furey, W, Gronenborn, A.M.
登録日2008-04-30
公開日2008-08-19
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping
Structure, 16, 2008
1IIY
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Solution NMR Structure of Complex of 1:2 Cyanovirin-N:Man-Alpha1,2-Man-Alpha Restrained Regularized Mean Coordinates
分子名称: CYANOVIRIN-N, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Bewley, C.A.
登録日2001-04-24
公開日2001-10-24
最終更新日2020-07-29
実験手法SOLUTION NMR
主引用文献Solution Structure of a Cyanovirin-N:Man alpha 1-2Man alpha Complex. Structural Basis for High Affinity Carbohydrate-Mediated Binding to gp120
Structure, 9, 2001
1J4V
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CYANOVIRIN-N
分子名称: CYANOVIRIN-N
著者Clore, G.M, Bewley, C.A.
登録日2001-11-21
公開日2002-03-06
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings.
J.Magn.Reson., 154, 2002
1L5B
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DOMAIN-SWAPPED CYANOVIRIN-N DIMER
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, cyanovirin-N
著者Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M.
登録日2002-03-06
公開日2002-05-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures.
Structure, 10, 2002
4J4E
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Structure of P51G Cyanovirin-N swapped trimer in the P212121 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4F
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Structure of P51G Cyanovirin-N swapped tetramer in the P212121 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4G
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Structure of P51G Cyanovirin-N swapped tetramer in the C2 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
1L5E
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The domain-swapped dimer of CV-N in solution
分子名称: Cyanovirin-N
著者Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M.
登録日2002-03-06
公開日2002-06-05
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures.
Structure, 10, 2002
4J4C
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Structure of P51G Cyanovirin-N swapped dimer in the P3221 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J4D
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Structure of P51G Cyanovirin-N swapped dimer in the P21212 space group
分子名称: Cyanovirin-N
著者Koharudin, L.M.I, Liu, L, Gronenborn, A.M.
登録日2013-02-06
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Proc.Natl.Acad.Sci.USA, 110, 2013
1LOM
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CYANOVIRIN-N DOUBLE MUTANT P51S S52P
分子名称: CALCIUM ION, Cyanovirin-N, SULFATE ION
著者Botos, I, Mori, T, Cartner, L.K, Boyd, M.R, Wlodawer, A.
登録日2002-05-06
公開日2002-06-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Domain-swapped structure of a mutant of cyanovirin-N.
Biochem.Biophys.Res.Commun., 294, 2002
3GXY
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Crystal structure of cyanovirin-n complexed to a synthetic hexamannoside
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
著者Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
登録日2009-04-03
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of the complexes of a potent anti-HIV protein cyanovirin-n and high mannose oligosaccharides
J.Biol.Chem., 277, 2002
3GXZ
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Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9)
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cyanovirin-N, MAGNESIUM ION, ...
著者Botos, I, O'Keefe, B.R, Shenoy, S.R, Seeberger, P.H, Boyd, M.R, Wlodawer, A.
登録日2009-04-03
公開日2009-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
J.Biol.Chem., 277, 2002

 

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