PDB: 114 件ウェブページステータス検索Chemie searchBIRD

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5MWW	Sigma1.1 domain of sigmaA from Bacillus subtilis 分子名称: RNA polymerase sigma factor SigA 著者 Zachrdla, M, Padrta, P, Rabatinova, A, Sanderova, H, Barvik, I, Krasny, L, Zidek, L. 登録日 2017-01-20 公開日 2017-06-14 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Solution structure of domain 1.1 of the sigma (A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase core. J. Biol. Chem., 292, 2017
2K6X	Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure 分子名称: RNA polymerase sigma factor rpoD 著者 Schwartz, E.C, Shekhtman, A, Dutta, K, Pratt, M.R, Cowburn, D, Darst, S, Muir, T.W. 登録日 2008-07-28 公開日 2008-10-28 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure Chem.Biol., 15, 2008
6VJS	Escherichia coli RNA polymerase and ureidothiophene-2-carboxylic acid complex 分子名称: 3-{[benzyl(ethyl)carbamoyl]amino}-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2020-01-17 公開日 2020-10-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.02 Å) 主引用文献 Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus -Based Wound Infection Model in SKH1 Mice. Acs Infect Dis., 6, 2020
8JO2	Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA 分子名称: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... 著者 Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. 登録日 2023-06-06 公開日 2023-08-30 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. Nucleic Acids Res., 51, 2023
8AD1	RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Dey, S, Weixlbaumer, A. 登録日 2022-07-07 公開日 2022-10-19 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into RNA-mediated transcription regulation in bacteria. Mol.Cell, 82, 2022
8FTD	Structure of Escherichia coli CedA in complex with transcription initiation complex 分子名称: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, M, Vassyliev, N, Nudler, E. 登録日 2023-01-11 公開日 2024-01-10 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 General transcription factor from Escherichia coli with a distinct mechanism of action. Nat.Struct.Mol.Biol., 31, 2024
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... 著者 Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. 登録日 2009-08-01 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (19.799999 Å) 主引用文献 Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
6B6H	The cryo-EM structure of a bacterial class I transcription activation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A. 登録日 2017-10-02 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of bacterial transcription activation. Science, 358, 2017
4MEY	Crystal structure of Escherichia coli RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.948 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
8X6F	Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex 分子名称: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yuan, L, Xu, L, Liu, Q, Feng, Y. 登録日 2023-11-21 公開日 2024-06-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
8Y6U	Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Shi, J. 登録日 2024-02-03 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 NMR analysis of a loop-bulge structure of UUCGA pentaloop. Biochem.Biophys.Res.Commun., 691, 2024
8IGR	Cryo-EM structure of CII-dependent transcription activation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. 登録日 2023-02-21 公開日 2023-05-17 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
8IGS	Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRE 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y. 登録日 2023-02-21 公開日 2023-05-17 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of lambda CII-dependent transcription activation. Structure, 31, 2023
4MEX	Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2014-06-25 実験手法 X-RAY DIFFRACTION (3.902 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
7F75	Cryo-EM structure of Spx-dependent transcription activation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-06-28 公開日 2021-10-13 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of transcription activation by the global regulator Spx. Nucleic Acids Res., 49, 2021
7KHE	Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp 分子名称: CHAPSO, DNA (46-MER), DNA (54-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-21 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
6JNX	Cryo-EM structure of a Q-engaged arrested complex 分子名称: Antiterminator Q protein, DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Feng, Y, Shi, J. 登録日 2019-03-18 公開日 2019-06-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.08 Å) 主引用文献 Structural basis of Q-dependent transcription antitermination. Nat Commun, 10, 2019
6K4Y	CryoEM structure of sigma appropriation complex 分子名称: 10 kDa anti-sigma factor, DNA (60-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Shi, J, Wen, A, Feng, Y. 登録日 2019-05-27 公開日 2019-08-07 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Structural basis of sigma appropriation. Nucleic Acids Res., 47, 2019
6LDI	The cryo-EM structure of E. coli CueR transcription activation complex 分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2019-11-21 公開日 2020-09-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 CueR activates transcription through a DNA distortion mechanism. Nat.Chem.Biol., 17, 2021
6P1K	Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-05-20 公開日 2020-02-26 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6P18	Q21 transcription antitermination complex: loading complex 分子名称: DNA (67-MER) fragment carrying phage-21 pR' promoter and pause element, nontemplate strand, template strand, ... 著者 Yin, Z, Ebright, R.H. 登録日 2019-05-19 公開日 2019-06-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis of Q-dependent antitermination. Proc.Natl.Acad.Sci.USA, 116, 2019
6PB4	The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.35 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
7SZK	Cryo-EM structure of 27a bound to E. coli RNAP and rrnBP1 promoter complex 分子名称: (2S,7R,7aR,13aP,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,21,23-trihydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-10-[4-(2-methylpropyl)piperazin-1-yl]-12-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1,6,15-trioxo-1,2,7,7a-tetrahydro-6H-2,7-(epoxypentadeca[1,11,13]trienoimino)[1]benzofuro[4,5-a]phenoxazin-25-yl acetate, DNA (5'-D(P*CP*TP*CP*GP*TP*AP*GP*AP*GP*TP*CP*CP*GP*TP*GP*TP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2021-11-28 公開日 2022-07-13 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis. Acs Infect Dis., 8, 2022
7UBM	Transcription antitermination complex: "pre-engaged" Qlambda-loading complex 分子名称: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ... 著者 Yin, Z, Ebright, R.H. 登録日 2022-03-15 公開日 2022-09-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022

 

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