PDB: 15 件ウェブページステータス検索Chemie searchBIRD

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4I9O	Crystal Structure of GACKIX L664C Tethered to 1-10 分子名称: 1,2-ETHANEDIOL, 1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one, CREB-binding protein 著者 Wang, N, Meagher, J.L, Stuckey, J.A, Mapp, A.K. 登録日 2012-12-05 公開日 2013-03-06 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ordering a dynamic protein via a small-molecule stabilizer. J.Am.Chem.Soc., 135, 2013
2KWF	The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1 分子名称: CREB-binding protein, Transcription factor 4 著者 Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P. 登録日 2010-04-08 公開日 2011-07-20 実験手法 SOLUTION NMR 主引用文献 The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1 To be Published
5U4K	NMR structure of the complex between the KIX domain of CBP and the transactivation domain 1 of p65 分子名称: CREB-binding protein, Transcription factor p65 著者 Lecoq, L, Raiola, L, Chabot, P.R, Cyr, N, Arseneault, G, Omichinski, J.G. 登録日 2016-12-05 公開日 2017-03-08 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-kappa B and transcription regulatory factors. Nucleic Acids Res., 45, 2017
2LQH	NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation) 分子名称: CREB-binding protein, Forkhead box O3 著者 Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. 登録日 2012-03-06 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment. Proc.Natl.Acad.Sci.USA, 109, 2012
2LQI	NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation) 分子名称: CREB-binding protein, Forkhead box O3 著者 Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. 登録日 2012-03-06 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment. Proc.Natl.Acad.Sci.USA, 109, 2012
2LXS	Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core 分子名称: CREB-binding protein, Histone-lysine N-methyltransferase MLL 著者 Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M. 登録日 2012-08-31 公開日 2013-06-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core. Acs Chem.Biol., 8, 2013
2AGH	Structural basis for cooperative transcription factor binding to the CBP coactivator 分子名称: Crebbp protein, Myb proto-oncogene protein, Zinc finger protein HRX 著者 De Guzman, R.N, Goto, N.K, Dyson, H.J, Wright, P.E. 登録日 2005-07-26 公開日 2005-11-22 最終更新日 2021-07-07 実験手法 SOLUTION NMR 主引用文献 Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator J.Mol.Biol., 355, 2006
1KDX	KIX DOMAIN OF MOUSE CBP (CREB BINDING PROTEIN) IN COMPLEX WITH PHOSPHORYLATED KINASE INDUCIBLE DOMAIN (PKID) OF RAT CREB (CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN), NMR 17 STRUCTURES 分子名称: CBP, CREB 著者 Radhakrishnan, I, Perez-Alvarado, G.C, Dyson, H.J, Wright, P.E. 登録日 1997-09-16 公開日 1998-11-25 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions. Cell(Cambridge,Mass.), 91, 1997
1SB0	Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb 分子名称: protein CBP, protein c-Myb 著者 Zor, T, De Guzman, R.N, Dyson, H.J, Wright, P.E. 登録日 2004-02-09 公開日 2004-04-13 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of c-Myb J.Mol.Biol., 337, 2004
6DMX	HBZ56 in complex with KIX and c-Myb 分子名称: BZIP factor, CREB-binding protein, Transcriptional activator Myb 著者 Yang, K, Wright, P.E, Stanfield, R.L. 登録日 2018-06-05 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DNQ	HBZ77 in complex with KIX and c-Myb 分子名称: 1,2-ETHANEDIOL, BZIP factor, CREB-binding protein, ... 著者 Yang, K, Wright, P.E, Stanfield, R.L. 登録日 2018-06-07 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5SVH	Crystal structure of the KIX domain of CBP in complex with a MLL/c-Myb chimera 分子名称: CHLORIDE ION, CREB-binding protein, GLYCEROL, ... 著者 Langelaan, D.N, Smith, S.P, Allingham, J.A. 登録日 2016-08-06 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Design of a nanomolar affinity ligand to the KIX domain of CBP To Be Published
2LXT	Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core 分子名称: CREB-binding protein, Cyclic AMP-responsive element-binding protein 1, Histone-lysine N-methyltransferase MLL 著者 Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M. 登録日 2012-08-31 公開日 2013-06-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core. Acs Chem.Biol., 8, 2013
7TB3	cryo-EM structure of MBP-KIX-apoferritin 分子名称: Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed 著者 Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. 登録日 2021-12-21 公開日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.57 Å) 主引用文献 Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. Acs Cent.Sci., 8, 2022
7TBH	cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7 分子名称: Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed, LEU-SER-ARG-ARG-PRO-SEP-TYR-ARG-LYS-ILE-LEU-ASN-ASP-LEU-SER-SER-ASP-ALA-PRO 著者 Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. 登録日 2021-12-22 公開日 2022-03-16 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. Acs Cent.Sci., 8, 2022