PDB: 657 件ウェブページステータス検索Chemie searchBIRD

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5OAK	Structure of the dmPar3 PDZ1 domain in complex with the dmPar6 PBM 分子名称: Bazooka, isoform C,LD29223p, GLYCEROL 著者 Bruekner, S.R, Wiesner, S. 登録日 2017-06-22 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for the interaction between the cell polarity proteins Par3 and Par6. Sci Signal, 11, 2018
8HU2	Rattus Syntenin-1 PDZ domain with inhibitor 分子名称: (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1 著者 Heo, Y, Lee, J, Yun, J.H, Lee, W. 登録日 2022-12-22 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution. To Be Published
8OEP	Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide 分子名称: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 著者 Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. 登録日 2023-03-11 公開日 2023-05-10 最終更新日 2023-05-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
4UU6	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. 登録日 2014-07-24 公開日 2015-01-14 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
1BFE	THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 分子名称: PSD-95 著者 Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. 登録日 1998-05-20 公開日 1998-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
1B8Q	SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE 分子名称: PROTEIN (HEPTAPEPTIDE), PROTEIN (NEURONAL NITRIC OXIDE SYNTHASE) 著者 Tochio, H, Zhang, Q, Mandal, P, Li, M, Zhang, M. 登録日 1999-02-01 公開日 1999-04-29 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide. Nat.Struct.Biol., 6, 1999
1BE9	THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT. 分子名称: CRIPT, PSD-95 著者 Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. 登録日 1998-05-20 公開日 1998-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
4UU5	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE 分子名称: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ... 著者 Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. 登録日 2014-07-24 公開日 2015-01-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
1D5G	SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE 分子名称: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV 著者 Kozlov, G, Gehring, K, Ekiel, I. 登録日 1999-10-07 公開日 2002-07-24 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions J.Mol.Biol., 320, 2002
4WYU	Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide 分子名称: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU 著者 Ren, J.Q, Pei, H.H, Feng, W. 登録日 2014-11-18 公開日 2015-10-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule. Biochem.J., 468, 2015
7CQF	Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ... 著者 Yamagata, A, Fukai, S. 登録日 2020-08-10 公開日 2021-01-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention. Proc.Natl.Acad.Sci.USA, 118, 2021
7D6F	The crystal structure of ARMS-PBM/MAGI2-PDZ4 分子名称: GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ... 著者 Ye, J, Zhang, Y, Zhong, Z, Wang, C. 登録日 2020-09-30 公開日 2020-11-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode. Neurochem.Int., 149, 2021
7VZE	Crystal structure of PTPN4 PDZ bound to the PBM of HPV16 E6 分子名称: Tyrosine-protein phosphatase non-receptor type 4, the PDZ-binding motif of HPV16 E6 著者 Lee, H.S, Yun, H.-Y, Ku, B. 登録日 2021-11-16 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.882 Å) 主引用文献 Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein. J.Microbiol, 60, 2022
1G9O	FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR 分子名称: NHE-RF 著者 Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. 登録日 2000-11-26 公開日 2001-05-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
7W71	Crystal structure of the PDZ-C domain of E. coli RseP in complex with 12C7 Fab 分子名称: Heavy chain of Fab, Light chain of Fab, Regulator of sigma-E protease RseP 著者 Hirose, T, Katagiri, S, Nogi, T. 登録日 2021-12-02 公開日 2022-09-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci Adv, 8, 2022
7E0B	The crystal structure of sorting nexin 27 and PBM complex 分子名称: PBM, Sorting nexin-27 著者 Shang, G.J, Qi, J.X. 登録日 2021-01-27 公開日 2022-02-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry. Proc.Natl.Acad.Sci.USA, 119, 2022
1GM1	Second PDZ Domain (PDZ2) of PTP-BL 分子名称: PROTEIN TYROSINE PHOSPHATASE 著者 Walma, T, Tessari, M, Aelen, J, Schepens, J, Hendriks, W, Vuister, G.W. 登録日 2001-09-06 公開日 2002-03-08 最終更新日 2018-03-28 実験手法 SOLUTION NMR 主引用文献 Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL. J. Mol. Biol., 316, 2002
5MZ7	Crystal Structure of the third PDZ domain from the synaptic protein PSD-95 with incorporated Azidohomoalanine 分子名称: Disks large homolog 4 著者 Kudlinzki, D, Lehner, F, Witt, K, Linhard, V.L, Silvers, R, Schwalbe, H. 登録日 2017-01-31 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. Chembiochem, 18, 2017
6EEY	Crystal structure of human Scribble PDZ4 R1110G Mutant 分子名称: Protein scribble homolog 著者 Janezic, E.M, Hsu, P, Hague, C. 登録日 2018-08-15 公開日 2019-10-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.145 Å) 主引用文献 Scribble co-operatively binds multiple alpha1D-adrenergic receptor C-terminal PDZ ligands. Sci Rep, 9, 2019
5ZDS	Crystal structure of the second PDZ domain of Frmpd2 分子名称: FERM and PDZ domain-containing 2 著者 Lu, X, Wang, X.F. 登録日 2018-02-24 公開日 2019-02-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors. Biochem.Biophys.Res.Commun., 516, 2019
6EZI	PDZK1 domain 4 in complex with C-terminal peptide of human PepT2. 分子名称: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2 著者 Loew, C, Flayhan, A, Pieprzyk, J. 登録日 2017-11-15 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.503321 Å) 主引用文献 Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018
5ZYS	Structure of Nephrin/MAGI1 complex 分子名称: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin 著者 Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G. 登録日 2018-05-28 公開日 2019-01-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling. J. Am. Soc. Nephrol., 29, 2018
6ESP	Proteome-wide analysis of phospho-regulated PDZ domain interactions 分子名称: Protein scribble homolog 著者 Chi, N.C. 登録日 2017-10-24 公開日 2018-09-05 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 Proteome-wide analysis of phospho-regulated PDZ domain interactions. Mol. Syst. Biol., 14, 2018
6AK2	Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 分子名称: Syntenin-1, peptide inhibitor KSL-128018 著者 Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. 登録日 2018-08-29 公開日 2019-09-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.868 Å) 主引用文献 A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J.Med.Chem., 64, 2021
6GBE	Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain-PRK2 Peptide Complex 分子名称: Serine/threonine-protein kinase N2, Tyrosine-protein phosphatase non-receptor type 13 著者 Kock, G, Stoll, R. 登録日 2018-04-13 公開日 2018-12-05 最終更新日 2020-01-29 実験手法 SOLUTION NMR 主引用文献 Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13. J. Mol. Biol., 430, 2018

 

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