1A25
 
 | | C2 DOMAIN FROM PROTEIN KINASE C (BETA) | | 分子名称: | CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA) | | 著者 | Sutton, R.B, Sprang, S.R. | | 登録日 | 1998-01-16 | | 公開日 | 1998-05-06 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998
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8C5H
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7A1R
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1K5W
 | | THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE | | 分子名称: | CALCIUM ION, Synaptotagmin I | | 著者 | Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J. | | 登録日 | 2001-10-12 | | 公開日 | 2002-01-23 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32, 2001
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4DNL
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1BCI
 | | C2 DOMAIN OF CYTOSOLIC PHOSPHOLIPASE A2, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | CALCIUM ION, CYTOSOLIC PHOSPHOLIPASE A2 | | 著者 | Xu, G.Y, Mcdonagh, T, Yu, H.A, Nalefski, E.A, Clark, J.D, Cumming, D.A. | | 登録日 | 1998-04-30 | | 公開日 | 1998-11-25 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and membrane interactions of the C2 domain of cytosolic phospholipase A2.
J.Mol.Biol., 280, 1998
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6U4W
 | | 1.4 A structure of a pathogenic human Syt 1 C2B (D366E) | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | | 登録日 | 2019-08-26 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
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1BYN
 | | SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I | | 分子名称: | CALCIUM ION, PROTEIN (SYNAPTOTAGMIN I) | | 著者 | Shao, X, Fernandez, I, Sudhof, T.C, Rizo, J. | | 登録日 | 1998-10-18 | | 公開日 | 1998-10-21 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
Biochemistry, 37, 1998
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4V29
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4WEE
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7ATP
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7AS6
 | | 2.0 angstrom structure of plant Extended Synaptotagmin 1, C2A domain | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | | 著者 | Benavente, J.L, Albert, A. | | 登録日 | 2020-10-27 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure and flexibility analysis of the Arabidopsis synaptotagmin 1 reveal the basis of its regulation at membrane contact sites.
Life Sci Alliance, 4, 2021
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4V11
 | | Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 | | 分子名称: | CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ... | | 著者 | Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R. | | 登録日 | 2014-09-22 | | 公開日 | 2015-02-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.
J.Neurosci., 35, 2015
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7JOF
 | | Calcium-bound C2A Domain from Human Dysferlin | | 分子名称: | CALCIUM ION, Isoform 6 of Dysferlin | | 著者 | Tadayon, R, Wang, Y, Santamaria, L, Mercier, P, Forristal, C, Shaw, G.S. | | 登録日 | 2020-08-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner.
Biochem.J., 478, 2021
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7K6B
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7KRB
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6TZ3
 | | Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B. | | 登録日 | 2019-08-09 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
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6U41
 | | 1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | | 登録日 | 2019-08-22 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
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6U4U
 | | 1.3 A structure of a pathogenic human Syt 1 C2B (I368T) | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | | 登録日 | 2019-08-26 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
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3RPB
 | | THE C2B-DOMAIN OF RABPHILIN: STRUCTURAL VARIATIONS IN A JANUS-FACED DOMAIN | | 分子名称: | RABPHILIN 3-A | | 著者 | Ubach, J, Garcia, J, Nittler, M.P, Sudhof, T.C, Rizo, J. | | 登録日 | 1999-04-19 | | 公開日 | 1999-12-23 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Janus-faced C2B domain of rabphilin.
Nat.Cell Biol., 1, 1999
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2UZP
 | | Crystal structure of the C2 domain of human protein kinase C gamma. | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, COBALT (II) ION, ... | | 著者 | Pike, A.C.W, Amos, A, Johansson, C, Sobott, F, Savitsky, P, Berridge, G, Fedorov, O, Umeano, C, Gorrec, F, Bunkoczi, G, Debreczeni, J, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. | | 登録日 | 2007-04-30 | | 公開日 | 2007-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of C2 Domain of Protein Kinase C Gamma
To be Published
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6NYT
 | | Munc13-1 C2B-domain, calcium bound | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | | 登録日 | 2019-02-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.369 Å) | | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Nat. Struct. Mol. Biol., 17, 2010
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6NYC
 | | Munc13-1 C2B-domain, calcium free | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Munc13-1 | | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | | 登録日 | 2019-02-11 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis.
Nat. Struct. Mol. Biol., 17, 2010
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3GPE
 | | Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2 | | 分子名称: | CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ... | | 著者 | Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N. | | 登録日 | 2009-03-23 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2.
Proc.Natl.Acad.Sci.USA, 106, 2009
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5CCJ
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