8W7C
Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:11923310 |
| Chain | Residue | Details |
| A | SER153 | |
| B | SER153 | |
| C | SER153 | |
| D | SER153 | |
| E | SER153 | |
| F | SER153 | |
| G | SER153 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS178 | |
| B | HIS178 | |
| C | HIS178 | |
| D | HIS178 | |
| E | HIS178 | |
| F | HIS178 | |
| G | HIS178 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:O88696 |
| Chain | Residue | Details |
| A | LYS200 | |
| B | LYS200 | |
| C | LYS200 | |
| D | LYS200 | |
| E | LYS200 | |
| F | LYS200 | |
| G | LYS200 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS211 | |
| B | LYS211 | |
| C | LYS211 | |
| D | LYS211 | |
| E | LYS211 | |
| F | LYS211 | |
| G | LYS211 |
