8FFE

Crystal structure of LRP6 E1E2 domains bound to YW210.09 Fab and engineered XWnt8 peptide

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR1194-HIS1200

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site_id	PS01186
Number of Residues	16
Details	EGF_2 EGF-like domain signature 2. CaCpiGFelisdmktC

Chain	Residue	Details
A	CYS612-CYS627

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	43
Details	Repeat: {"description":"LDL-receptor class B 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	42
Details	Repeat: {"description":"LDL-receptor class B 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	43
Details	Repeat: {"description":"LDL-receptor class B 3"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	42
Details	Repeat: {"description":"LDL-receptor class B 4"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	39
Details	Repeat: {"description":"LDL-receptor class B 5"}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	42
Details	Domain: {"description":"EGF-like 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	42
Details	Repeat: {"description":"LDL-receptor class B 6"}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	42
Details	Repeat: {"description":"LDL-receptor class B 7"}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	43
Details	Repeat: {"description":"LDL-receptor class B 8"}

Chain

Residue

Details

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site_id	SWS_FT_FI10
Number of Residues	40
Details	Repeat: {"description":"LDL-receptor class B 9"}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	41
Details	Repeat: {"description":"LDL-receptor class B 10"}

Chain

Residue

Details

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site_id	SWS_FT_FI12
Number of Residues	40
Details	Domain: {"description":"EGF-like 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI13
Number of Residues	255
Details	Region: {"description":"Beta-propeller 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI14
Number of Residues	261
Details	Region: {"description":"Beta-propeller 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI15
Number of Residues	5
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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