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8CXC

Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics

Functional Information from PROSITE/UniProt
site_idPS00024
Number of Residues15
DetailsHEMOPEXIN Hemopexin domain signature. FYkkWel.EaCVDAAL
ChainResidueDetails
MPHE317-LEU331

site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
LTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
MASN388
MASN496
MASN523

237735

PDB entries from 2025-06-18

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