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8AV2

Crystal structure for the FnIII module of mouse LEP-R in complex with the anti-LEP-R nanobody VHH-4.80

Functional Information from GO Data
ChainGOidnamespacecontents
A0004896molecular_functioncytokine receptor activity
A0016020cellular_componentmembrane
B0004896molecular_functioncytokine receptor activity
B0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS01353
Number of Residues57
DetailsHEMATOPO_REC_L_F2 Long hematopoietin receptor, gp130 family signature. NslgaSlvnfqltfswpmskvsaveslsayplssscvi...LsWtlsPddysll...YlvIeW
ChainResidueDetails
AASN716-TRP772

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues184
DetailsDomain: {"description":"Fibronectin type-III 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues12
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

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PDB entries from 2025-12-17

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