7KMT

Structure of the yeast TRAPPIII-Ypt1(Rab1) complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000045	biological_process	autophagosome assembly
A	0000139	cellular_component	Golgi membrane
A	0000149	molecular_function	SNARE binding
A	0000407	cellular_component	phagophore assembly site
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005795	cellular_component	Golgi stack
A	0005801	cellular_component	cis-Golgi network
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
A	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A	0006914	biological_process	autophagy
A	0012505	cellular_component	endomembrane system
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0016236	biological_process	macroautophagy
A	0031410	cellular_component	cytoplasmic vesicle
A	0032258	biological_process	cytoplasm to vacuole targeting by the Cvt pathway
A	0032456	biological_process	endocytic recycling
A	0034045	cellular_component	phagophore assembly site membrane
A	0034497	biological_process	protein localization to phagophore assembly site
A	0034498	biological_process	early endosome to Golgi transport
A	0035493	biological_process	SNARE complex assembly
A	0035494	biological_process	SNARE complex disassembly
A	0048194	biological_process	Golgi vesicle budding
A	0048211	biological_process	Golgi vesicle docking
A	0061709	biological_process	reticulophagy
A	0090114	biological_process	COPII-coated vesicle budding
A	1900101	biological_process	regulation of endoplasmic reticulum unfolded protein response
A	1990261	biological_process	pre-mRNA catabolic process
B	0000045	biological_process	autophagosome assembly
B	0000407	cellular_component	phagophore assembly site
B	0000425	biological_process	pexophagy
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
B	0006914	biological_process	autophagy
B	0016236	biological_process	macroautophagy
B	0030435	biological_process	sporulation resulting in formation of a cellular spore
B	0031410	cellular_component	cytoplasmic vesicle
B	0032258	biological_process	cytoplasm to vacuole targeting by the Cvt pathway
B	0034497	biological_process	protein localization to phagophore assembly site
B	0034727	biological_process	piecemeal microautophagy of the nucleus
B	0051321	biological_process	meiotic cell cycle
B	0071255	biological_process	Cvt vesicle assembly
B	1990072	cellular_component	TRAPPIII protein complex
E	0000407	cellular_component	phagophore assembly site
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0005783	cellular_component	endoplasmic reticulum
E	0005794	cellular_component	Golgi apparatus
E	0005801	cellular_component	cis-Golgi network
E	0005802	cellular_component	trans-Golgi network
E	0005829	cellular_component	cytosol
E	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
E	0006891	biological_process	intra-Golgi vesicle-mediated transport
E	0006914	biological_process	autophagy
E	0016192	biological_process	vesicle-mediated transport
E	0016236	biological_process	macroautophagy
E	0016239	biological_process	positive regulation of macroautophagy
E	0030008	cellular_component	TRAPP complex
E	0031503	biological_process	protein-containing complex localization
E	0034497	biological_process	protein localization to phagophore assembly site
E	0042147	biological_process	retrograde transport, endosome to Golgi
E	0043087	biological_process	regulation of GTPase activity
E	0048193	biological_process	Golgi vesicle transport
E	0065003	biological_process	protein-containing complex assembly
E	1990070	cellular_component	TRAPPI protein complex
E	1990071	cellular_component	TRAPPII protein complex
E	1990072	cellular_component	TRAPPIII protein complex
F	0000407	cellular_component	phagophore assembly site
F	0005085	molecular_function	guanyl-nucleotide exchange factor activity
F	0005515	molecular_function	protein binding
F	0005783	cellular_component	endoplasmic reticulum
F	0005794	cellular_component	Golgi apparatus
F	0005829	cellular_component	cytosol
F	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
F	0006891	biological_process	intra-Golgi vesicle-mediated transport
F	0006914	biological_process	autophagy
F	0006995	biological_process	cellular response to nitrogen starvation
F	0016192	biological_process	vesicle-mediated transport
F	0016236	biological_process	macroautophagy
F	0030008	cellular_component	TRAPP complex
F	0032258	biological_process	cytoplasm to vacuole targeting by the Cvt pathway
F	0033106	cellular_component	cis-Golgi network membrane
F	0042147	biological_process	retrograde transport, endosome to Golgi
F	0048193	biological_process	Golgi vesicle transport
F	1990070	cellular_component	TRAPPI protein complex
F	1990071	cellular_component	TRAPPII protein complex
F	1990072	cellular_component	TRAPPIII protein complex
G	0000407	cellular_component	phagophore assembly site
G	0005085	molecular_function	guanyl-nucleotide exchange factor activity
G	0005515	molecular_function	protein binding
G	0005783	cellular_component	endoplasmic reticulum
G	0005794	cellular_component	Golgi apparatus
G	0005829	cellular_component	cytosol
G	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
G	0006891	biological_process	intra-Golgi vesicle-mediated transport
G	0006914	biological_process	autophagy
G	0016192	biological_process	vesicle-mediated transport
G	0016236	biological_process	macroautophagy
G	0030008	cellular_component	TRAPP complex
G	0042147	biological_process	retrograde transport, endosome to Golgi
G	0048193	biological_process	Golgi vesicle transport
G	1990070	cellular_component	TRAPPI protein complex
G	1990071	cellular_component	TRAPPII protein complex
G	1990072	cellular_component	TRAPPIII protein complex
H	0000407	cellular_component	phagophore assembly site
H	0005085	molecular_function	guanyl-nucleotide exchange factor activity
H	0005515	molecular_function	protein binding
H	0005783	cellular_component	endoplasmic reticulum
H	0005794	cellular_component	Golgi apparatus
H	0005829	cellular_component	cytosol
H	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
H	0006891	biological_process	intra-Golgi vesicle-mediated transport
H	0006914	biological_process	autophagy
H	0016192	biological_process	vesicle-mediated transport
H	0016236	biological_process	macroautophagy
H	0030008	cellular_component	TRAPP complex
H	0042147	biological_process	retrograde transport, endosome to Golgi
H	0048193	biological_process	Golgi vesicle transport
H	0051276	biological_process	chromosome organization
H	1990070	cellular_component	TRAPPI protein complex
H	1990071	cellular_component	TRAPPII protein complex
H	1990072	cellular_component	TRAPPIII protein complex
I	0000407	cellular_component	phagophore assembly site
I	0005085	molecular_function	guanyl-nucleotide exchange factor activity
I	0005515	molecular_function	protein binding
I	0005783	cellular_component	endoplasmic reticulum
I	0005794	cellular_component	Golgi apparatus
I	0005829	cellular_component	cytosol
I	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
I	0006891	biological_process	intra-Golgi vesicle-mediated transport
I	0006914	biological_process	autophagy
I	0006995	biological_process	cellular response to nitrogen starvation
I	0016192	biological_process	vesicle-mediated transport
I	0016236	biological_process	macroautophagy
I	0030008	cellular_component	TRAPP complex
I	0032258	biological_process	cytoplasm to vacuole targeting by the Cvt pathway
I	0033106	cellular_component	cis-Golgi network membrane
I	0042147	biological_process	retrograde transport, endosome to Golgi
I	0048193	biological_process	Golgi vesicle transport
I	1990070	cellular_component	TRAPPI protein complex
I	1990071	cellular_component	TRAPPII protein complex
I	1990072	cellular_component	TRAPPIII protein complex
J	0000407	cellular_component	phagophore assembly site
J	0005085	molecular_function	guanyl-nucleotide exchange factor activity
J	0005515	molecular_function	protein binding
J	0005783	cellular_component	endoplasmic reticulum
J	0005794	cellular_component	Golgi apparatus
J	0005829	cellular_component	cytosol
J	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
J	0006891	biological_process	intra-Golgi vesicle-mediated transport
J	0006914	biological_process	autophagy
J	0016192	biological_process	vesicle-mediated transport
J	0016236	biological_process	macroautophagy
J	0030008	cellular_component	TRAPP complex
J	0042147	biological_process	retrograde transport, endosome to Golgi
J	0048193	biological_process	Golgi vesicle transport
J	1990070	cellular_component	TRAPPI protein complex
J	1990071	cellular_component	TRAPPII protein complex
J	1990072	cellular_component	TRAPPIII protein complex
K	0000407	cellular_component	phagophore assembly site
K	0003674	molecular_function	molecular_function
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005783	cellular_component	endoplasmic reticulum
K	0005794	cellular_component	Golgi apparatus
K	0005829	cellular_component	cytosol
K	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
K	0006891	biological_process	intra-Golgi vesicle-mediated transport
K	0006914	biological_process	autophagy
K	0012505	cellular_component	endomembrane system
K	0016192	biological_process	vesicle-mediated transport
K	0016236	biological_process	macroautophagy
K	0030008	cellular_component	TRAPP complex
K	0042147	biological_process	retrograde transport, endosome to Golgi
K	0043229	cellular_component	intracellular organelle
K	0065003	biological_process	protein-containing complex assembly
K	1990070	cellular_component	TRAPPI protein complex
K	1990071	cellular_component	TRAPPII protein complex
K	1990072	cellular_component	TRAPPIII protein complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:14576435, ECO:0000269|PubMed:16034420, ECO:0000269|PubMed:16395334, ECO:0007744|PDB:1UKV, ECO:0007744|PDB:1YZN, ECO:0007744|PDB:2BCG

Chain	Residue	Details
A	SER17
A	TYR33
A	ASN121
A	ALA152

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16034420, ECO:0007744|PDB:1YZN

Chain	Residue	Details
A	GLY66

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000269|Ref.5

Chain	Residue	Details
A	MET1

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	SER172

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
A	SER174

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site_id	SWS_FT_FI6
Number of Residues	2
Details	LIPID: S-palmitoyl cysteine => ECO:0000255

Chain	Residue	Details
A	CYS23
A	CYS123

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site_id	SWS_FT_FI7
Number of Residues	1
Details	LIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:10071213, ECO:0000269|PubMed:16395334

Chain	Residue	Details
A	CYS205

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site_id	SWS_FT_FI8
Number of Residues	1
Details	LIPID: S-geranylgeranyl cysteine => ECO:0000269|PubMed:10071213, ECO:0000269|PubMed:14576435, ECO:0000269|PubMed:16395334, ECO:0007744|PDB:1UKV

Chain	Residue	Details
A	CYS206

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site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047

Chain	Residue	Details
A	LYS144

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