7F3O
Crystal structure of the GluA2o LBD in complex with glutamate and TAK-653
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| E | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| E | 0016020 | cellular_component | membrane |
| F | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| F | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20614889, ECO:0007744|PDB:2XHD |
| Chain | Residue | Details |
| A | PRO499 | |
| C | THR501 | |
| C | SER675 | |
| C | THR676 | |
| D | PRO499 | |
| D | THR501 | |
| D | SER675 | |
| D | THR676 | |
| E | PRO499 | |
| E | THR501 | |
| E | SER675 | |
| A | THR501 | |
| E | THR676 | |
| F | PRO499 | |
| F | THR501 | |
| F | SER675 | |
| F | THR676 | |
| A | SER675 | |
| A | THR676 | |
| B | PRO499 | |
| B | THR501 | |
| B | SER675 | |
| B | THR676 | |
| C | PRO499 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20614889, ECO:0000269|PubMed:21531559, ECO:0007744|PDB:2XHD, ECO:0007744|PDB:3R7X |
| Chain | Residue | Details |
| A | ARG506 | |
| B | ARG506 | |
| C | ARG506 | |
| D | ARG506 | |
| E | ARG506 | |
| F | ARG506 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20614889, ECO:0000269|PubMed:21531559, ECO:0007744|PDB:2XHD |
| Chain | Residue | Details |
| A | GLU726 | |
| B | GLU726 | |
| C | GLU726 | |
| D | GLU726 | |
| E | GLU726 | |
| F | GLU726 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000250|UniProtKB:P19491 |
| Chain | Residue | Details |
| A | SER683 | |
| B | SER683 | |
| C | SER683 | |
| D | SER683 | |
| E | SER683 | |
| F | SER683 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine; by PKG => ECO:0000250|UniProtKB:P19491 |
| Chain | Residue | Details |
| A | SER717 | |
| B | SER717 | |
| C | SER717 | |
| D | SER717 | |
| E | SER717 | |
| F | SER717 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN413 | |
| B | ASN413 | |
| C | ASN413 | |
| D | ASN413 | |
| E | ASN413 | |
| F | ASN413 |
