7AL7
The Crystal Structure of Human IL-18 in Complex With Human IL-18 Binding Protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042007 | molecular_function | interleukin-18 binding |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0006954 | biological_process | inflammatory response |
| B | 0006955 | biological_process | immune response |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 101 |
| Details | Domain: {"description":"Ig-like C2-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"22171320","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by CASP3","evidences":[{"source":"PubMed","id":"37993714","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9334240","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
