7A17
Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016791 | molecular_function | phosphatase activity |
| A | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
| C | 0016791 | molecular_function | phosphatase activity |
| C | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
| E | 0016791 | molecular_function | phosphatase activity |
| E | 0046856 | biological_process | phosphatidylinositol dephosphorylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01427","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33349335","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7A0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7A17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01427","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33349335","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7A0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7A17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33349335","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7A17","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q8CHC4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
