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6WVZ

Crystal structure of anti-MET Fab arm of amivantamab in complex with human MET

Functional Information from GO Data
ChainGOidnamespacecontents
M0017154molecular_functionsemaphorin receptor activity
M0071526biological_processsemaphorin-plexin signaling pathway
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
HTYR200-HIS206
LTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Cleavage => ECO:0000255
ChainResidueDetails
MARG307

site_idSWS_FT_FI2
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
MASN45
MASN149
MASN202
MASN399
MASN405

site_idSWS_FT_FI3
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19196183
ChainResidueDetails
MASN106

227111

PDB entries from 2024-11-06

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