Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6WDQ

IL23/IL23R/IL12Rb1 signaling complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0004896molecular_functioncytokine receptor activity
A0016020cellular_componentmembrane
B0001916biological_processpositive regulation of T cell mediated cytotoxicity
B0002230biological_processpositive regulation of defense response to virus by host
B0002827biological_processpositive regulation of T-helper 1 type immune response
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005788cellular_componentendoplasmic reticulum lumen
B0006954biological_processinflammatory response
B0006955biological_processimmune response
B0007259biological_processcell surface receptor signaling pathway via JAK-STAT
B0032693biological_processnegative regulation of interleukin-10 production
B0032725biological_processpositive regulation of granulocyte macrophage colony-stimulating factor production
B0032729biological_processpositive regulation of type II interferon production
B0032733biological_processpositive regulation of interleukin-10 production
B0032735biological_processpositive regulation of interleukin-12 production
B0032740biological_processpositive regulation of interleukin-17 production
B0032760biological_processpositive regulation of tumor necrosis factor production
B0032816biological_processpositive regulation of natural killer cell activation
B0032819biological_processpositive regulation of natural killer cell proliferation
B0034105biological_processpositive regulation of tissue remodeling
B0042098biological_processT cell proliferation
B0042102biological_processpositive regulation of T cell proliferation
B0042104biological_processpositive regulation of activated T cell proliferation
B0043382biological_processpositive regulation of memory T cell differentiation
B0045087biological_processinnate immune response
B0045519molecular_functioninterleukin-23 receptor binding
B0045672biological_processpositive regulation of osteoclast differentiation
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0048771biological_processtissue remodeling
B0050729biological_processpositive regulation of inflammatory response
B0050829biological_processdefense response to Gram-negative bacterium
B0051135biological_processpositive regulation of NK T cell activation
B0051142biological_processpositive regulation of NK T cell proliferation
B0051607biological_processdefense response to virus
B0070743cellular_componentinterleukin-23 complex
B0090023biological_processpositive regulation of neutrophil chemotaxis
B0097696biological_processcell surface receptor signaling pathway via STAT
B1901224biological_processpositive regulation of non-canonical NF-kappaB signal transduction
B2000318biological_processpositive regulation of T-helper 17 type immune response
B2000330biological_processpositive regulation of T-helper 17 cell lineage commitment
Functional Information from PROSITE/UniProt
site_idPS00092
Number of Residues7
DetailsN6_MTASE N-6 Adenine-specific DNA methylases signature. CFQDPPY
ChainResidueDetails
DCYS30-TYR36

site_idPS01354
Number of Residues43
DetailsHEMATOPO_REC_L_F3 Long hematopoietin receptor, soluble alpha chains family signature. IkPDPPknLqlkplknsrq.VevsWeyPdTWstphsyFsLtFcV
ChainResidueDetails
AILE233-VAL275

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
DASN121
CASN273

site_idSWS_FT_FI2
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21053369
ChainResidueDetails
CASN47
CASN81
CASN141
CASN232
CASN262

site_idSWS_FT_FI3
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine => ECO:0000269|PubMed:21053369
ChainResidueDetails
CASN180

225681

PDB entries from 2024-10-02

PDB statisticsPDBj update infoContact PDBjnumon