Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0036211 | biological_process | protein modification process |
B | 0036211 | biological_process | protein modification process |
C | 0036211 | biological_process | protein modification process |
D | 0036211 | biological_process | protein modification process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | binding site for residue ADP A 601 |
Chain | Residue |
A | LYS125 |
A | LEU203 |
A | TYR204 |
A | ILE205 |
A | LYS215 |
A | ASP217 |
A | HIS261 |
A | THR263 |
A | ASN264 |
A | ASP346 |
A | LEU348 |
A | PRO147 |
A | LEU358 |
A | GLU359 |
A | RZY602 |
A | MG603 |
A | MG604 |
A | ILE172 |
A | LYS174 |
A | ALA179 |
A | ARG180 |
A | GLY181 |
A | ILE184 |
A | GLN202 |
site_id | AC2 |
Number of Residues | 22 |
Details | binding site for residue RZY A 602 |
Chain | Residue |
A | TYR69 |
A | ALA179 |
A | ARG180 |
A | ARG219 |
A | TYR221 |
A | LEU239 |
A | ARG241 |
A | ASN264 |
A | TYR265 |
A | SER266 |
A | LYS283 |
A | ASP346 |
A | GLU359 |
A | ASN361 |
A | SER363 |
A | PRO364 |
A | SER365 |
A | ASP373 |
A | LYS377 |
A | ADP601 |
A | MG603 |
A | MG604 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue MG A 603 |
Chain | Residue |
A | ARG241 |
A | ASN264 |
A | ASP346 |
A | GLU359 |
A | ADP601 |
A | RZY602 |
A | MG604 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue MG A 604 |
Chain | Residue |
A | LYS125 |
A | GLU359 |
A | ASN361 |
A | ADP601 |
A | RZY602 |
A | MG603 |
site_id | AC5 |
Number of Residues | 23 |
Details | binding site for residue ADP B 601 |
Chain | Residue |
B | LYS125 |
B | ILE172 |
B | LYS174 |
B | ALA179 |
B | ARG180 |
B | GLY181 |
B | ILE184 |
B | GLN202 |
B | LEU203 |
B | TYR204 |
B | ILE205 |
B | LYS215 |
B | ASP217 |
B | LEU262 |
B | THR263 |
B | ASN264 |
B | ASP346 |
B | LEU348 |
B | LEU358 |
B | GLU359 |
B | RZP604 |
B | MG605 |
B | MG606 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue GOL B 602 |
Chain | Residue |
B | ARG68 |
B | TYR69 |
B | ASP70 |
B | SER367 |
B | THR368 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue GOL B 603 |
Chain | Residue |
B | LYS169 |
B | LEU203 |
B | GOL608 |
site_id | AC8 |
Number of Residues | 22 |
Details | binding site for residue RZP B 604 |
Chain | Residue |
B | LYS283 |
B | ASP346 |
B | GLU359 |
B | ASN361 |
B | SER363 |
B | PRO364 |
B | SER365 |
B | LYS377 |
B | ADP601 |
B | MG605 |
B | MG606 |
B | GOL607 |
D | LYS194 |
B | TYR69 |
B | ALA179 |
B | ARG180 |
B | ARG219 |
B | LEU239 |
B | ARG241 |
B | ASN264 |
B | TYR265 |
B | SER266 |
site_id | AC9 |
Number of Residues | 6 |
Details | binding site for residue MG B 605 |
Chain | Residue |
B | ARG241 |
B | ASN264 |
B | ASP346 |
B | GLU359 |
B | ADP601 |
B | RZP604 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue MG B 606 |
Chain | Residue |
B | GLU359 |
B | ASN361 |
B | ADP601 |
B | RZP604 |
site_id | AD2 |
Number of Residues | 4 |
Details | binding site for residue GOL B 607 |
Chain | Residue |
B | ARG68 |
B | SER363 |
B | RZP604 |
D | GLU192 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue GOL B 608 |
Chain | Residue |
B | HIS144 |
B | PHE146 |
B | ARG148 |
B | GOL603 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for residue GOL B 609 |
Chain | Residue |
B | TYR235 |
B | ASN236 |
B | ASN290 |
B | TRP304 |
B | ARG445 |
B | GOL610 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue GOL B 610 |
Chain | Residue |
B | LYS294 |
B | GLU301 |
B | TRP304 |
B | ARG305 |
B | GOL609 |
site_id | AD6 |
Number of Residues | 9 |
Details | binding site for residue GOL B 611 |
Chain | Residue |
B | PHE214 |
B | PHE242 |
B | ALA243 |
B | THR244 |
B | ASN273 |
B | SER280 |
B | GLY281 |
B | SER282 |
B | ARG284 |
site_id | AD7 |
Number of Residues | 23 |
Details | binding site for residue ADP C 601 |
Chain | Residue |
C | LYS125 |
C | ILE172 |
C | LYS174 |
C | ALA179 |
C | ARG180 |
C | GLY181 |
C | ILE184 |
C | GLN202 |
C | LEU203 |
C | TYR204 |
C | ILE205 |
C | LYS215 |
C | ASP217 |
C | HIS261 |
C | THR263 |
C | ASN264 |
C | ASP346 |
C | LEU348 |
C | LEU358 |
C | GLU359 |
C | RZP602 |
C | MG603 |
C | MG604 |
site_id | AD8 |
Number of Residues | 23 |
Details | binding site for residue RZP C 602 |
Chain | Residue |
A | LYS194 |
C | TYR69 |
C | GLY178 |
C | ALA179 |
C | ARG180 |
C | ARG219 |
C | TYR221 |
C | ARG241 |
C | ASN264 |
C | TYR265 |
C | SER266 |
C | LYS283 |
C | ASP346 |
C | GLU359 |
C | ASN361 |
C | ILE362 |
C | SER363 |
C | PRO364 |
C | SER365 |
C | LYS377 |
C | ADP601 |
C | MG603 |
C | MG604 |
site_id | AD9 |
Number of Residues | 8 |
Details | binding site for residue MG C 603 |
Chain | Residue |
C | LYS125 |
C | GLY178 |
C | ALA179 |
C | ARG180 |
C | GLU359 |
C | ASN361 |
C | ADP601 |
C | RZP602 |
site_id | AE1 |
Number of Residues | 6 |
Details | binding site for residue MG C 604 |
Chain | Residue |
C | ARG241 |
C | ASN264 |
C | ASP346 |
C | GLU359 |
C | ADP601 |
C | RZP602 |
site_id | AE2 |
Number of Residues | 1 |
Details | binding site for residue GOL C 605 |
site_id | AE3 |
Number of Residues | 25 |
Details | binding site for residue ADP D 601 |
Chain | Residue |
D | LYS125 |
D | ILE172 |
D | LYS174 |
D | ALA179 |
D | ARG180 |
D | GLY181 |
D | ILE184 |
D | GLN202 |
D | LEU203 |
D | TYR204 |
D | ILE205 |
D | LYS215 |
D | ASP217 |
D | HIS261 |
D | LEU262 |
D | THR263 |
D | ASN264 |
D | ASP346 |
D | LEU348 |
D | LEU358 |
D | GLU359 |
D | RZP602 |
D | MG603 |
D | MG604 |
D | HOH701 |
site_id | AE4 |
Number of Residues | 26 |
Details | binding site for residue RZP D 602 |
Chain | Residue |
B | LYS194 |
D | TYR69 |
D | ARG180 |
D | ARG219 |
D | TYR221 |
D | LEU239 |
D | ARG241 |
D | ASN264 |
D | TYR265 |
D | SER266 |
D | LYS283 |
D | ASP346 |
D | GLU359 |
D | ASN361 |
D | ILE362 |
D | SER363 |
D | PRO364 |
D | SER365 |
D | LYS377 |
D | ADP601 |
D | MG603 |
D | MG604 |
D | GOL611 |
D | HOH701 |
D | HOH702 |
D | HOH704 |
site_id | AE5 |
Number of Residues | 7 |
Details | binding site for residue MG D 603 |
Chain | Residue |
D | ASP346 |
D | GLU359 |
D | ASN361 |
D | ADP601 |
D | RZP602 |
D | MG604 |
D | HOH701 |
site_id | AE6 |
Number of Residues | 5 |
Details | binding site for residue MG D 604 |
Chain | Residue |
D | GLU359 |
D | ASN361 |
D | ADP601 |
D | RZP602 |
D | MG603 |
site_id | AE7 |
Number of Residues | 2 |
Details | binding site for residue GOL D 605 |
Chain | Residue |
D | LYS294 |
D | TYR298 |
site_id | AE8 |
Number of Residues | 2 |
Details | binding site for residue GOL D 606 |
Chain | Residue |
D | ASP309 |
D | LYS455 |
site_id | AE9 |
Number of Residues | 7 |
Details | binding site for residue GOL D 607 |
Chain | Residue |
D | PHE214 |
D | PHE242 |
D | ALA243 |
D | SER280 |
D | GLY281 |
D | SER282 |
D | ARG284 |
site_id | AF1 |
Number of Residues | 4 |
Details | binding site for residue GOL D 608 |
Chain | Residue |
D | ASP212 |
D | TYR292 |
D | HIS296 |
D | GOL609 |
site_id | AF2 |
Number of Residues | 5 |
Details | binding site for residue GOL D 609 |
Chain | Residue |
D | ILE210 |
D | ASP212 |
D | GLY213 |
D | GOL608 |
D | GOL613 |
site_id | AF3 |
Number of Residues | 4 |
Details | binding site for residue GOL D 610 |
Chain | Residue |
D | GLU301 |
D | TRP304 |
D | ARG305 |
D | ARG445 |
site_id | AF4 |
Number of Residues | 4 |
Details | binding site for residue GOL D 611 |
Chain | Residue |
B | LYS194 |
D | ARG68 |
D | TYR97 |
D | RZP602 |
site_id | AF5 |
Number of Residues | 3 |
Details | binding site for residue GOL D 612 |
Chain | Residue |
D | LEU203 |
D | ILE205 |
D | GOL614 |
site_id | AF6 |
Number of Residues | 4 |
Details | binding site for residue GOL D 613 |
Chain | Residue |
D | PHE209 |
D | ILE210 |
D | ARG351 |
D | GOL609 |
site_id | AF7 |
Number of Residues | 4 |
Details | binding site for residue GOL D 614 |
Chain | Residue |
D | HIS144 |
D | ARG148 |
D | TRP356 |
D | GOL612 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LYS174 | |
C | GLN202 | |
C | LYS215 | |
C | THR263 | |
D | LYS174 | |
D | GLN202 | |
D | LYS215 | |
D | THR263 | |
A | GLN202 | |
A | LYS215 | |
A | THR263 | |
B | LYS174 | |
B | GLN202 | |
B | LYS215 | |
B | THR263 | |
C | LYS174 | |
Chain | Residue | Details |
A | ARG180 | |
A | ILE362 | |
B | ARG180 | |
B | ILE362 | |
C | ARG180 | |
C | ILE362 | |
D | ARG180 | |
D | ILE362 | |
Chain | Residue | Details |
A | ARG241 | |
B | LYS377 | |
C | ARG241 | |
C | TYR265 | |
C | SER266 | |
C | LYS283 | |
C | LYS377 | |
D | ARG241 | |
D | TYR265 | |
D | SER266 | |
D | LYS283 | |
A | TYR265 | |
D | LYS377 | |
A | SER266 | |
A | LYS283 | |
A | LYS377 | |
B | ARG241 | |
B | TYR265 | |
B | SER266 | |
B | LYS283 | |
Chain | Residue | Details |
A | ASP346 | |
D | ASP346 | |
D | GLU359 | |
D | ASN361 | |
A | GLU359 | |
A | ASN361 | |
B | ASP346 | |
B | GLU359 | |
B | ASN361 | |
C | ASP346 | |
C | GLU359 | |
C | ASN361 | |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | SITE: Essential for specifying alpha-elongation versus initiation step of the polyglutamylase activity => ECO:0000269|PubMed:32747782 |
Chain | Residue | Details |
A | ARG180 | |
B | ARG180 | |
C | ARG180 | |
D | ARG180 | |
site_id | SWS_FT_FI6 |
Number of Residues | 4 |
Details | SITE: Important for specifying alpha-elongation versus initiation step of the polyglutamylase activity => ECO:0000269|PubMed:32747782 |
Chain | Residue | Details |
A | ILE362 | |
B | ILE362 | |
C | ILE362 | |
D | ILE362 | |