Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004252 | molecular_function | serine-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue J6T A 301 |
| Chain | Residue |
| A | LEU41 |
| A | THR214 |
| A | SER215 |
| A | ARG218 |
| A | VAL219 |
| A | GLY226 |
| A | ILE227 |
| A | HOH401 |
| D | ASP61 |
| A | HIS57 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | LYS192 |
| A | GLY193 |
| A | ASP194 |
| A | SER195 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue J6T B 301 |
| Chain | Residue |
| B | LEU41 |
| B | CYS42 |
| B | HIS57 |
| B | ASP189 |
| B | SER190 |
| B | CYS191 |
| B | LYS192 |
| B | GLY193 |
| B | ASP194 |
| B | SER195 |
| B | THR214 |
| B | SER215 |
| B | ARG218 |
| B | VAL219 |
| B | CYS220 |
| B | GLY226 |
| B | ILE227 |
| B | HOH406 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for residue J6T C 301 |
| Chain | Residue |
| B | ASP61 |
| C | LEU41 |
| C | HIS57 |
| C | ASP189 |
| C | SER190 |
| C | CYS191 |
| C | LYS192 |
| C | GLY193 |
| C | ASP194 |
| C | SER195 |
| C | VAL213 |
| C | THR214 |
| C | SER215 |
| C | ARG218 |
| C | VAL219 |
| C | CYS220 |
| C | GLY226 |
| C | ILE227 |
| C | HOH428 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue J6T D 301 |
| Chain | Residue |
| D | LEU41 |
| D | CYS42 |
| D | HIS57 |
| D | ASP189 |
| D | SER190 |
| D | CYS191 |
| D | LYS192 |
| D | GLY193 |
| D | ASP194 |
| D | SER195 |
| D | THR214 |
| D | SER215 |
| D | ARG218 |
| D | CYS220 |
| D | GLY226 |
| D | ILE227 |
| D | HOH406 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue J6T E 301 |
| Chain | Residue |
| E | HIS57 |
| E | ASP189 |
| E | SER190 |
| E | CYS191 |
| E | LYS192 |
| E | GLY193 |
| E | ASP194 |
| E | SER195 |
| E | VAL213 |
| E | THR214 |
| E | SER215 |
| E | ARG218 |
| E | VAL219 |
| E | CYS220 |
| E | GLY226 |
| E | ILE227 |
| E | HOH409 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue J6T F 301 |
| Chain | Residue |
| F | ARG218 |
| F | VAL219 |
| F | CYS220 |
| F | GLY226 |
| F | ILE227 |
| F | HOH401 |
| F | HIS57 |
| F | ASP189 |
| F | SER190 |
| F | CYS191 |
| F | LYS192 |
| F | GLY193 |
| F | ASP194 |
| F | SER195 |
| F | VAL213 |
| F | THR214 |
| F | SER215 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| D | HIS57 | |
| D | ASP102 | |
| D | SER195 | |
| E | HIS57 | |
| E | ASP102 | |
| E | SER195 | |
| F | HIS57 | |
| F | ASP102 | |
| F | SER195 | |
| A | ASP102 | |
| A | SER195 | |
| B | HIS57 | |
| B | ASP102 | |
| B | SER195 | |
| C | HIS57 | |
| C | ASP102 | |
| C | SER195 | |
