6NIP

Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0046983	molecular_function	protein dimerization activity
Z	0046983	molecular_function	protein dimerization activity

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
A	TYR194-HIS200
B	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Region: {"description":"Fusion peptide","evidences":[{"source":"UniProtKB","id":"P14336","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"PubMed","id":"27093288","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27338953","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27882950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29091758","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"A0A142I5B9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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