6H8K

Crystal structure of a variant (Q133C in PSST) of Yarrowia lipolytica complex I

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003954	molecular_function	NADH dehydrogenase activity
1	0005743	cellular_component	mitochondrial inner membrane
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0009060	biological_process	aerobic respiration
1	0016020	cellular_component	membrane
1	0022904	biological_process	respiratory electron transport chain
1	0045271	cellular_component	respiratory chain complex I
1	1902600	biological_process	proton transmembrane transport
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0042773	biological_process	ATP synthesis coupled electron transport
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0042773	biological_process	ATP synthesis coupled electron transport
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0022904	biological_process	respiratory electron transport chain
6	0031966	cellular_component	mitochondrial membrane
6	1902600	biological_process	proton transmembrane transport
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0048038	molecular_function	quinone binding
C	0051287	molecular_function	NAD binding
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
I	0016020	cellular_component	membrane
I	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0048038	molecular_function	quinone binding
K	0051536	molecular_function	iron-sulfur cluster binding
K	0051539	molecular_function	4 iron, 4 sulfur cluster binding
L	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
L	0042773	biological_process	ATP synthesis coupled electron transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue FES A 900

Chain	Residue
A	CYS69
A	CYS80
A	CYS97

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SF4 A 901

Chain	Residue
A	CYS133
A	CYS136
A	ASP137
A	CYS142

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SF4 A 902

Chain	Residue
A	CYS186
A	THR187
A	CYS189
A	CYS183
A	ILE184

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SF4 B 500

Chain	Residue
B	CYS381
B	GLY382
B	CYS384
B	CYS387
B	CYS427
B	LEU429

---

site_id	AC5
Number of Residues	6
Details	binding site for residue FES H 300

Chain	Residue
H	CYS127
H	PRO131
H	CYS132
H	CYS168
H	GLY170
H	CYS172

---

site_id	AC6
Number of Residues	9
Details	binding site for residue SF4 I 500

Chain	Residue
I	CYS140
I	CYS169
I	ILE170
I	TYR171
I	CYS172
I	GLY173
I	TYR174
I	CYS175
I	GLU186

---

site_id	AC7
Number of Residues	7
Details	binding site for residue SF4 I 501

Chain	Residue
I	CYS130
I	CYS133
I	CYS136
I	TYR162
I	CYS179
I	VAL181
I	ILE184

---

site_id	AC8
Number of Residues	7
Details	binding site for residue SF4 K 500

Chain	Residue
K	CYS85
K	CYS86
K	GLY121
K	SER149
K	CYS150
K	CYS180
K	PRO181

---

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP

Chain	Residue	Details
I	CYS130-PRO141
I	CYS169-PRO180

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQaFaDAVKLLlKE

Chain	Residue	Details
1	GLY46-GLU61

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTESEseLVa.G

Chain	Residue	Details
1	PRO201-GLY214

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREayDMYgvffegHpdlRrIM

Chain	Residue	Details
G	GLU179-MET200

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
C	LEU119-LYS130

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDVYvPgCPP

Chain	Residue	Details
K	GLY166-PRO182

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPvCDqGGeCdLQ

Chain	Residue	Details
A	CYS133-GLN145

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	440
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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