6GMX
pVHL:EloB:EloC in complex with 6-chlorothiochroman-4-one
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| A | 0030891 | cellular_component | VCB complex |
| A | 0070449 | cellular_component | elongin complex |
| B | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| D | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| D | 0030891 | cellular_component | VCB complex |
| D | 0070449 | cellular_component | elongin complex |
| E | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| G | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| G | 0030891 | cellular_component | VCB complex |
| G | 0070449 | cellular_component | elongin complex |
| H | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| J | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| J | 0030891 | cellular_component | VCB complex |
| J | 0070449 | cellular_component | elongin complex |
| K | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue F7B B 201 |
| Chain | Residue |
| B | GLU64 |
| B | ILE65 |
| B | PRO66 |
| B | GLU102 |
| B | PHE109 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue IPA C 301 |
| Chain | Residue |
| C | HIS115 |
| C | TRP117 |
| C | TRP88 |
| C | TYR98 |
| C | HIS110 |
| C | SER111 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue IPA F 301 |
| Chain | Residue |
| F | TRP88 |
| F | TYR98 |
| F | SER111 |
| F | TYR112 |
| F | HIS115 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue ACT F 302 |
| Chain | Residue |
| F | ARG82 |
| F | ARG161 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue IPA I 301 |
| Chain | Residue |
| I | TYR98 |
| I | HIS110 |
| I | SER111 |
| I | HIS115 |
| I | TRP117 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue F7B K 201 |
| Chain | Residue |
| K | GLU64 |
| K | PRO66 |
| K | GLU102 |
| K | MET105 |
| K | PHE109 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue IPA L 301 |
| Chain | Residue |
| L | TRP88 |
| L | TYR98 |
| L | HIS110 |
| L | SER111 |
| L | HIS115 |
| L | TRP117 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue ACT L 302 |
| Chain | Residue |
| L | ARG82 |
| L | ARG161 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| D | MET1 | |
| G | MET1 | |
| J | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P62869 |
| Chain | Residue | Details |
| D | THR84 | |
| G | THR84 | |
| J | THR84 |
