Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| B | 0016579 | biological_process | protein deubiquitination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 1001 |
| Chain | Residue |
| A | GLN219 |
| A | ARG262 |
| A | GLY275 |
| A | THR276 |
| A | LYS277 |
| A | LYS278 |
| A | HOH1233 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1002 |
| Chain | Residue |
| A | SER341 |
| A | LYS391 |
| A | HOH1140 |
| A | SER330 |
| A | TYR331 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue CQ5 A 1003 |
| Chain | Residue |
| A | TYR224 |
| A | ASP295 |
| A | VAL296 |
| A | GLN297 |
| A | LEU406 |
| A | MET407 |
| A | ARG408 |
| A | PHE409 |
| A | LYS420 |
| A | HIS456 |
| A | ASN460 |
| A | HIS461 |
| A | TYR465 |
| A | TYR514 |
| A | HOH1159 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 1001 |
| Chain | Residue |
| B | GLY275 |
| B | THR276 |
| B | LYS277 |
| B | LYS278 |
| B | HOH1103 |
| B | HOH1132 |
| B | HOH1154 |
| B | HOH1229 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1002 |
| Chain | Residue |
| B | GLY475 |
| B | THR489 |
| B | LYS490 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue CQ5 B 1003 |
| Chain | Residue |
| B | TYR224 |
| B | ASP295 |
| B | VAL296 |
| B | GLN297 |
| B | LEU406 |
| B | MET407 |
| B | ARG408 |
| B | PHE409 |
| B | LYS420 |
| B | HIS456 |
| B | ASN460 |
| B | HIS461 |
| B | TYR465 |
| B | TYR514 |
| B | HOH1199 |
Functional Information from PROSITE/UniProt
| site_id | PS00972 |
| Number of Residues | 16 |
| Details | USP_1 Ubiquitin specific protease (USP) domain signature 1. GLknqGAtCYMNSlLQ |
| Chain | Residue | Details |
| A | GLY215-GLN230 | |
| site_id | PS00973 |
| Number of Residues | 18 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YiLhAVlvHsGdnhg..GHY |
| Chain | Residue | Details |
| A | TYR448-TYR465 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS223 | |
| B | CYS223 | |
| Chain | Residue | Details |
| A | HIS464 | |
| B | HIS464 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 789 |
| Chain | Residue | Details |
| A | ASN218 | electrostatic stabiliser |
| A | CYS223 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | HIS464 | proton acceptor, proton donor |
| A | ASP481 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 789 |
| Chain | Residue | Details |
| B | ASN218 | electrostatic stabiliser |
| B | CYS223 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | HIS464 | proton acceptor, proton donor |
| B | ASP481 | electrostatic stabiliser |
