6BDZ
ADAM10 Extracellular Domain Bound by the 11G2 Fab
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TFAHEVGHNF |
| Chain | Residue | Details |
| A | THR380-PHE389 |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
| Chain | Residue | Details |
| L | TYR215-HIS221 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:29224781, ECO:0000269|PubMed:29430990 |
| Chain | Residue | Details |
| A | GLU384 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24055016, ECO:0000269|PubMed:29224781, ECO:0000269|PubMed:37516108, ECO:0007744|PDB:6BDZ, ECO:0007744|PDB:6BE6, ECO:0007744|PDB:8ESV |
| Chain | Residue | Details |
| A | HIS383 | |
| A | HIS393 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29224781, ECO:0000269|PubMed:37516108, ECO:0007744|PDB:6BE6, ECO:0007744|PDB:8ESV |
| Chain | Residue | Details |
| A | HIS387 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN267 | |
| A | GLN439 | |
| A | GLN551 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:29224781, ECO:0007744|PDB:6BDZ, ECO:0007744|PDB:6BE6 |
| Chain | Residue | Details |
| A | ASN278 |
