6BDZ

ADAM10 Extracellular Domain Bound by the 11G2 Fab

Summary for 6BDZ

Entry DOI	10.2210/pdb6bdz/pdb
Descriptor	11G2 Fab Light Chain, 11G2 Fab Heavy Chain, Disintegrin and metalloproteinase domain-containing protein 10, ... (9 entities in total)
Functional Keywords	adam10, membrane protein
Biological source	Mus musculus More
Total number of polymer chains	3
Total formula weight	98129.64
Authors	Seegar, T.C.M. (deposition date: 2017-10-24, release date: 2017-12-27, Last modification date: 2020-07-29)
Primary citation	Seegar, T.C.M.,Killingsworth, L.B.,Saha, N.,Meyer, P.A.,Patra, D.,Zimmerman, B.,Janes, P.W.,Rubinstein, E.,Nikolov, D.B.,Skiniotis, G.,Kruse, A.C.,Blacklow, S.C. Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10. Cell, 171:1638-1648.e7, 2017 Cited by PubMed: 29224781 DOI: 10.1016/j.cell.2017.11.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation