6BDZ
ADAM10 Extracellular Domain Bound by the 11G2 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | 11G2 Fab Light Chain | polymer | 215 | 23455.9 | 1 | Mus musculus | ||
| 2 | B (H) | 11G2 Fab Heavy Chain | polymer | 226 | 24097.1 | 1 | Mus musculus | ||
| 3 | C (A) | Disintegrin and metalloproteinase domain-containing protein 10 | polymer | 443 | 48943.7 | 1 | UniProt (O14672) Pfam (PF13574) Pfam (PF00200) Pfam (PF21299) | Homo sapiens (Human) | ADAM 10,CDw156,Kuzbanian protein homolog,Mammalian disintegrin-metalloprotease |
| 4 | D (B) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G04854NQ) | |||
| 5 | E (C) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 6 | F, G (L) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | H (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | I (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 9 | J (H) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 220 - 654 (UniProt: O14672)
| PDB | External Database | Details |
|---|---|---|
| Gln 267 | Asn 267 | conflict |
| Gln 439 | Asn 439 | conflict |
| Gln 551 | Asn 551 | conflict |
| Gly 655 | - | expression tag |
| Gly 656 | - | expression tag |
| His 657 | - | expression tag |
| His 658 | - | expression tag |
| His 659 | - | expression tag |
| His 660 | - | expression tag |
| His 661 | - | expression tag |
| His 662 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96496.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1335.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 297.6 | |
| All* | Total formula weight | 98129.6 |
