5ZK5
Stapled-peptides tailored against initiation of translation
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue MGT A 1001 |
| Chain | Residue |
| A | TRP56 |
| A | HOH1122 |
| A | GLN57 |
| A | MET101 |
| A | TRP102 |
| A | GLU103 |
| A | ARG157 |
| A | LYS162 |
| A | HOH1103 |
| A | HOH1109 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residues MK8 B 101 and NH2 B 17 |
| Chain | Residue |
| A | LYS192 |
| B | MK812 |
| B | PHE13 |
| B | ARG15 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residues MK8 B 101 and MK8 B 12 |
| Chain | Residue |
| A | LYS192 |
| A | VAL194 |
| B | GLU8 |
| B | GLN9 |
| B | LEU10 |
| B | LEU11 |
| B | PHE13 |
| B | GLN14 |
| B | ARG15 |
| B | NH217 |
Functional Information from PROSITE/UniProt
| site_id | PS00813 |
| Number of Residues | 24 |
| Details | IF4E Eukaryotic initiation factor 4E signature. DYslFKdgIePmWEDeknkrGGRW |
| Chain | Residue | Details |
| A | ASP90-TRP113 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Region: {"description":"EIF4EBP1/2/3 binding","evidences":[{"source":"PubMed","id":"16271312","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11879179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12975586","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16271312","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"(Microbial infection) Interaction with potato virus Y VPg","evidences":[{"source":"PubMed","id":"31712417","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Region: {"description":"EIF4E-binding"} |
| Chain | Residue | Details |
