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5VK0

Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
C0005634cellular_componentnucleus
C0043066biological_processnegative regulation of apoptotic process
C0051726biological_processregulation of cell cycle
E0005634cellular_componentnucleus
E0043066biological_processnegative regulation of apoptotic process
E0051726biological_processregulation of cell cycle
G0005634cellular_componentnucleus
G0043066biological_processnegative regulation of apoptotic process
G0051726biological_processregulation of cell cycle
I0005634cellular_componentnucleus
I0043066biological_processnegative regulation of apoptotic process
I0051726biological_processregulation of cell cycle
K0005634cellular_componentnucleus
K0043066biological_processnegative regulation of apoptotic process
K0051726biological_processregulation of cell cycle
M0005634cellular_componentnucleus
M0043066biological_processnegative regulation of apoptotic process
M0051726biological_processregulation of cell cycle
O0005634cellular_componentnucleus
O0043066biological_processnegative regulation of apoptotic process
O0051726biological_processregulation of cell cycle
Q0005634cellular_componentnucleus
Q0043066biological_processnegative regulation of apoptotic process
Q0051726biological_processregulation of cell cycle
S0005634cellular_componentnucleus
S0043066biological_processnegative regulation of apoptotic process
S0051726biological_processregulation of cell cycle
U0005634cellular_componentnucleus
U0043066biological_processnegative regulation of apoptotic process
U0051726biological_processregulation of cell cycle
W0005634cellular_componentnucleus
W0043066biological_processnegative regulation of apoptotic process
W0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues1
Detailsbinding site for residue CL C 201
ChainResidue
CLEU33

site_idAC2
Number of Residues1
Detailsbinding site for residue CL X 101
ChainResidue
XSER11

225158

PDB entries from 2024-09-18

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