5TX4

Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005026	molecular_function	transforming growth factor beta receptor activity, type II
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
A	0016020	cellular_component	membrane
A	0046872	molecular_function	metal ion binding
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IhePkgYnanfCaGaC

Chain	Residue	Details
B	ILE33-CYS48

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN47
A	ASN71

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