5MG3
EM fitted model of bacterial holo-translocon
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0005515 | molecular_function | protein binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006457 | biological_process | protein folding |
| C | 0015031 | biological_process | protein transport |
| C | 0016020 | cellular_component | membrane |
| C | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| C | 0032977 | molecular_function | membrane insertase activity |
| C | 0043952 | biological_process | protein transport by the Sec complex |
| C | 0051205 | biological_process | protein insertion into membrane |
| C | 0065003 | biological_process | protein-containing complex assembly |
| D | 0005515 | molecular_function | protein binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006605 | biological_process | protein targeting |
| D | 0006886 | biological_process | intracellular protein transport |
| D | 0015031 | biological_process | protein transport |
| D | 0015450 | molecular_function | protein-transporting ATPase activity |
| D | 0016020 | cellular_component | membrane |
| D | 0043952 | biological_process | protein transport by the Sec complex |
| D | 0065002 | biological_process | intracellular protein transmembrane transport |
| E | 0005515 | molecular_function | protein binding |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0006605 | biological_process | protein targeting |
| E | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| E | 0006886 | biological_process | intracellular protein transport |
| E | 0008320 | molecular_function | protein transmembrane transporter activity |
| E | 0009306 | biological_process | protein secretion |
| E | 0015031 | biological_process | protein transport |
| E | 0016020 | cellular_component | membrane |
| E | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| E | 0043952 | biological_process | protein transport by the Sec complex |
| E | 0065002 | biological_process | intracellular protein transmembrane transport |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0006605 | biological_process | protein targeting |
| F | 0006886 | biological_process | intracellular protein transport |
| F | 0015031 | biological_process | protein transport |
| F | 0015450 | molecular_function | protein-transporting ATPase activity |
| F | 0016020 | cellular_component | membrane |
| F | 0043952 | biological_process | protein transport by the Sec complex |
| F | 0065002 | biological_process | intracellular protein transmembrane transport |
| G | 0005515 | molecular_function | protein binding |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| G | 0006886 | biological_process | intracellular protein transport |
| G | 0008320 | molecular_function | protein transmembrane transporter activity |
| G | 0009306 | biological_process | protein secretion |
| G | 0015031 | biological_process | protein transport |
| G | 0015450 | molecular_function | protein-transporting ATPase activity |
| G | 0016020 | cellular_component | membrane |
| G | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| G | 0043952 | biological_process | protein transport by the Sec complex |
| G | 0065002 | biological_process | intracellular protein transmembrane transport |
| Y | 0005048 | molecular_function | signal sequence binding |
| Y | 0005515 | molecular_function | protein binding |
| Y | 0005886 | cellular_component | plasma membrane |
| Y | 0006605 | biological_process | protein targeting |
| Y | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
| Y | 0006886 | biological_process | intracellular protein transport |
| Y | 0008320 | molecular_function | protein transmembrane transporter activity |
| Y | 0015031 | biological_process | protein transport |
| Y | 0016020 | cellular_component | membrane |
| Y | 0031522 | cellular_component | cell envelope Sec protein transport complex |
| Y | 0043952 | biological_process | protein transport by the Sec complex |
| Y | 0065002 | biological_process | intracellular protein transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00755 |
| Number of Residues | 20 |
| Details | SECY_1 Protein secY signature 1. SIFaLGImPYIsASIIIQLL |
| Chain | Residue | Details |
| Y | SER76-LEU95 |
| site_id | PS00756 |
| Number of Residues | 18 |
| Details | SECY_2 Protein secY signature 2. WLgEqITer.GIGNGiSII |
| Chain | Residue | Details |
| Y | TRP173-ILE190 |
| site_id | PS01067 |
| Number of Residues | 29 |
| Details | SECE_SEC61G Protein secE/sec61-gamma signature. FaREaRteVrKviWPtrqEtlhttLIVAA |
| Chain | Residue | Details |
| E | PHE452-ALA480 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 212 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 35 |
| Details | Transmembrane: {"description":"Discontinuously helical; Name=2","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | Intramembrane: {"description":"Helical; Name=Helix 2A","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Intramembrane: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 19 |
| Details | Intramembrane: {"description":"Helical; Name=Helix 2B","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 15 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 87 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 13 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 16 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 13 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 13 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 15 |
| Details | Transmembrane: {"description":"Helical; Name=8","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 14 |
| Details | Transmembrane: {"description":"Helical; Name=9","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 16 |
| Details | Transmembrane: {"description":"Helical; Name=10","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 187 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 11 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"2050112","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 147 |
| Details | Region: {"description":"Required for protein export"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 122 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 111 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 35 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI23 |
| Number of Residues | 56 |
| Details | Topological domain: {"description":"Cytoplasmic"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI24 |
| Number of Residues | 18 |
| Details | Topological domain: {"description":"Periplasmic"} |
| Chain | Residue | Details |
