Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001784 | molecular_function | phosphotyrosine residue binding |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
| A | 0023051 | biological_process | regulation of signaling |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | LEU328 |
| A | ASN346 |
| A | PRO347 |
| A | ASP348 |
| A | LEU349 |
| A | HOH635 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | CYS419 |
| A | CYS396 |
| A | HIS398 |
| A | CYS416 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 503 |
| Chain | Residue |
| A | CYS381 |
| A | CYS384 |
| A | CYS401 |
| A | CYS404 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 504 |
| Chain | Residue |
| A | ASP229 |
| A | THR231 |
| A | ASN233 |
| A | TYR235 |
| A | GLU240 |
| A | HOH667 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHlMCtsCL |
| Chain | Residue | Details |
| A | CYS396-LEU405 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 72 |
| Details | Region: {"description":"EF-hand-like"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 102 |
| Details | Region: {"description":"SH2-like"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1B47","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CBL","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine; by INSR","evidences":[{"source":"PubMed","id":"11997497","evidenceCode":"ECO:0000269"}]} |
