5FOE

Crystal structure of the C. elegans Protein O-fucosyltransferase 2 (CePOFUT2) double mutant (R298K-R299K) in complex with GDP and the human TSR1 from thrombospondin 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0036066	biological_process	protein O-linked glycosylation via fucose
A	0046922	molecular_function	peptide-O-fucosyltransferase activity
B	0036066	biological_process	protein O-linked glycosylation via fucose
B	0046922	molecular_function	peptide-O-fucosyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Glycosylation: {"description":"C-linked (Man) tryptophan","featureId":"CAR_000205","evidences":[{"source":"PubMed","id":"11067851","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (Fuc...) serine","featureId":"CAR_000206","evidences":[{"source":"PubMed","id":"11067851","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9Y2G5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26854667","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FOE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Site: {"description":"Essential for catalytic activity","evidences":[{"source":"UniProtKB","id":"Q9Y2G5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17761667","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26854667","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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