Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004520 | molecular_function | DNA endonuclease activity |
| B | 0004527 | molecular_function | exonuclease activity |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 1401 |
| Chain | Residue |
| B | ASP483 |
| B | LYS484 |
| B | GLY485 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 201 |
| Chain | Residue |
| A | G21 |
| A | U22 |
| B | ARG403 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 101 |
| Chain | Residue |
| C | DC8 |
| B | ASP1332 |
| B | ARG1333 |
| C | DG7 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 151 |
| Details | Domain: {"description":"HNH Cas9-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01085","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 662 |
| Details | Region: {"description":"Recognition lobe","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 17 |
| Details | Region: {"description":"ARM","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 47 |
| Details | Region: {"description":"RuvC-II","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 177 |
| Details | Region: {"description":"RuvC-III","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Motif: {"description":"PAM substrate-binding","evidences":[{"source":"PubMed","id":"25079318","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For RuvC-like nuclease domain","evidences":[{"source":"PubMed","id":"24529477","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor for HNH nuclease domain","evidences":[{"source":"PubMed","id":"24529477","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000269"}]} |
