Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue 5T2 A 1201 |
| Chain | Residue |
| A | VAL848 |
| A | CYS919 |
| A | LEU1019 |
| A | HIS1026 |
| A | LEU1035 |
| A | ILE1044 |
| A | CYS1045 |
| A | ASP1046 |
| A | PHE1047 |
| A | ALA866 |
| A | LYS868 |
| A | GLU885 |
| A | VAL898 |
| A | VAL899 |
| A | VAL914 |
| A | VAL916 |
| A | GLU917 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue 5T2 B 1201 |
| Chain | Residue |
| B | ALA866 |
| B | LYS868 |
| B | GLU885 |
| B | ILE892 |
| B | VAL898 |
| B | VAL899 |
| B | VAL914 |
| B | VAL916 |
| B | GLU917 |
| B | CYS919 |
| B | LEU1019 |
| B | HIS1026 |
| B | LEU1035 |
| B | ILE1044 |
| B | CYS1045 |
| B | ASP1046 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 29 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGAFGQVIeAdafgidktatcrt.....VAVK |
| Chain | Residue | Details |
| A | LEU840-LYS868 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNILL |
| Chain | Residue | Details |
| A | CYS1024-LEU1036 | |
| site_id | PS00240 |
| Number of Residues | 14 |
| Details | RECEPTOR_TYR_KIN_III Receptor tyrosine kinase class III signature. GhHlNVVNLLGACT |
| Chain | Residue | Details |
| A | GLY893-THR906 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
