Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for Ligand residues PTR B 378 through THR B 379 bound to THR B 377 |
| Chain | Residue |
| A | ARG32 |
| B | GLU380 |
| B | HOH501 |
| B | HOH502 |
| B | HOH503 |
| B | HOH504 |
| B | HOH505 |
| A | SER34 |
| A | LYS35 |
| A | SER36 |
| A | THR42 |
| A | THR52 |
| A | HIS53 |
| A | GLU90 |
| B | THR377 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for Ligand residues PTR C 378 through THR C 379 bound to THR C 377 |
| Chain | Residue |
| A | ARG138 |
| A | SER140 |
| A | GLN141 |
| A | SER142 |
| A | VAL148 |
| A | THR168 |
| A | HIS169 |
| A | MET171 |
| C | THR377 |
| C | GLU380 |
| C | HOH501 |
| C | HOH502 |
| C | HOH503 |
| C | HOH504 |
| C | HOH507 |
| C | HOH511 |
| C | HOH512 |
| C | HOH514 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Domain: {"description":"SH2 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P35235","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
