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4UDC

GR in complex with dexamethasone

Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE CPS A 1777
ChainResidue
ATRP557
ATRP610
AASP638
ATYR660
ATYR735
AGLN738
AMET745
AGLN776

site_idAC2
Number of Residues14
DetailsBINDING SITE FOR RESIDUE DEX A 1778
ChainResidue
ALEU563
AASN564
AGLY567
AGLN570
AMET604
AARG611
APHE623
AGLN642
ATYR735
ACYS736
ATHR739
AILE747
APHE749
AMET560

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues165
DetailsRegion: {"description":"Interaction with CRY1","evidences":[{"source":"PubMed","id":"22170608","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"12144530","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues4
DetailsMotif: {"description":"LXXLL motif 3"}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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