4TU7

Structure of U2AF65 D231V variant with BrU5 DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue DIO A 401

Chain	Residue
A	TYR269
A	ASN271

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site_id	AC2
Number of Residues	4
Details	binding site for residue DIO A 402

Chain	Residue
A	PRO144
A	TYR232
A	GLN233
A	LEU325

---

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 403

Chain	Residue
A	HOH589
A	LYS225
A	ARG227
A	HOH577

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 404

Chain	Residue
A	ARG150
A	GLU201
A	SER281
A	HOH515
A	HOH537
P	DU7

---

site_id	AC5
Number of Residues	1
Details	binding site for residue SO4 A 405

Chain	Residue
A	ARG228

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL A 406

Chain	Residue
A	ILE191
A	ASN192
A	GLN193
A	ASP194
B	LYS329

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	164
Details	Domain: {"description":"RRM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"5-hydroxylysine; by JMJD6","evidences":[{"source":"PubMed","id":"19574390","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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