4S10

Gelsolin nanobody shielding mutant plasma gelsolin from furin proteolysis

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0051015	molecular_function	actin filament binding
D	0051015	molecular_function	actin filament binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA C 301

Chain	Residue
C	GLY186
C	ASP187
C	GLU209
C	ASP259

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA D 301

Chain	Residue
D	GLY186
D	ASP187
D	GLU209
D	ASP259
D	HOH405

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
C	ARG161
D	ARG161

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:19666512, ECO:0007744|PDB:3FFK

Chain	Residue	Details
C	GLY186
C	ASP187
C	GLU209
C	ASP259
D	GLY186
D	ASP187
D	GLU209
D	ASP259

---