Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001730 | molecular_function | 2'-5'-oligoadenylate synthetase activity |
| A | 0002376 | biological_process | immune system process |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003725 | molecular_function | double-stranded RNA binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005829 | cellular_component | cytosol |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0045071 | biological_process | negative regulation of viral genome replication |
| A | 0045087 | biological_process | innate immune response |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
| A | 0060700 | biological_process | regulation of ribonuclease activity |
| A | 1904188 | biological_process | negative regulation of transformation of host cell by virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | ASP74 |
| A | ASP76 |
| A | MG402 |
| A | APC403 |
| A | HOH543 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | APC403 |
| A | ASP74 |
| A | ASP76 |
| A | ASP147 |
| A | MG401 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE APC A 403 |
| Chain | Residue |
| A | GLY61 |
| A | SER62 |
| A | LYS65 |
| A | SER73 |
| A | ASP74 |
| A | ASP76 |
| A | SER186 |
| A | GLN193 |
| A | LYS212 |
| A | GLN229 |
| A | TYR230 |
| A | MG401 |
| A | MG402 |
| A | HOH521 |
| A | HOH543 |
| A | HOH553 |
Functional Information from PROSITE/UniProt
| site_id | PS00832 |
| Number of Residues | 20 |
| Details | 25A_SYNTH_1 2'-5'-oligoadenylate synthases signature 1. GSsGKgTtLRgrsDaDLVvF |
| Chain | Residue | Details |
| A | GLY61-PHE80 | |
| site_id | PS00833 |
| Number of Residues | 11 |
| Details | 25A_SYNTH_2 2'-5'-oligoadenylate synthases signature 2. RPVILDPaDPT |
| Chain | Residue | Details |
| A | ARG295-THR305 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP147 | |
| A | GLN229 | |
| A | SER62 | |
| A | ASP74 | |
| A | ASP76 | |
| Chain | Residue | Details |
| A | ARG209 | |
| Chain | Residue | Details |
| A | LYS212 | |
| Chain | Residue | Details |
| A | GLN157 | |
