4HD0
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 401 |
| Chain | Residue |
| A | ASP49 |
| A | ASN84 |
| A | HIS173 |
| A | HIS206 |
| A | MN402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 402 |
| Chain | Residue |
| A | MN401 |
| A | ASP8 |
| A | HIS10 |
| A | ASP49 |
| A | HIS208 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 401 |
| Chain | Residue |
| B | ASP8 |
| B | HIS10 |
| B | ASP49 |
| B | HIS208 |
| B | MN402 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 402 |
| Chain | Residue |
| B | ASP8 |
| B | ASP49 |
| B | ASN84 |
| B | HIS173 |
| B | HIS206 |
| B | MN401 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_02044, ECO:0000305|PubMed:11371344, ECO:0000305|PubMed:15047855 |
| Chain | Residue | Details |
| A | HIS85 | |
| B | HIS85 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11371344, ECO:0000269|PubMed:15047855, ECO:0000269|PubMed:18854158, ECO:0000269|PubMed:23080121, ECO:0007744|PDB:1II7, ECO:0007744|PDB:1S8E, ECO:0007744|PDB:3DSD, ECO:0007744|PDB:4HD0 |
| Chain | Residue | Details |
| A | ASP8 | |
| B | ASP49 | |
| B | ASN84 | |
| B | HIS173 | |
| B | HIS206 | |
| B | HIS208 | |
| A | HIS10 | |
| A | ASP49 | |
| A | ASN84 | |
| A | HIS173 | |
| A | HIS206 | |
| A | HIS208 | |
| B | ASP8 | |
| B | HIS10 |
