4HD0
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
Summary for 4HD0
Entry DOI | 10.2210/pdb4hd0/pdb |
Descriptor | DNA double-strand break repair protein Mre11, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | nuclease enzyme, double-strand break repair, rad50, nbs1, mutation l204r, dna binding protein |
Biological source | Pyrococcus furiosus |
Total number of polymer chains | 2 |
Total formula weight | 79822.74 |
Authors | Limbo, O.,Moiani, D.,Kertokalio, A.,Wyman, C.,Tainer, J.A.,Russell, P. (deposition date: 2012-10-01, release date: 2012-10-31, Last modification date: 2024-02-28) |
Primary citation | Limbo, O.,Moiani, D.,Kertokalio, A.,Wyman, C.,Tainer, J.A.,Russell, P. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair. Nucleic Acids Res., 40:11435-11449, 2012 Cited by PubMed: 23080121DOI: 10.1093/nar/gks954 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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