Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | CYS1163 |
| A | CYS1164 |
| A | HIS1255 |
| A | CYS1258 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2 |
| Chain | Residue |
| A | CYS1247 |
| A | CYS1250 |
| A | CYS1272 |
| A | CYS1275 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 3 |
| Chain | Residue |
| A | CYS1183 |
| A | CYS1201 |
| A | CYS1204 |
| A | CYS1177 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 4 |
| Chain | Residue |
| A | HIS1315 |
| A | CYS1408 |
| B | HIS1315 |
| B | CYS1408 |
| site_id | AC5 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 01K A 700 |
| Chain | Residue |
| A | SER1396 |
| A | TYR1397 |
| A | LEU1398 |
| A | ASP1399 |
| A | SER1400 |
| A | LYS1407 |
| A | ARG1410 |
| A | THR1411 |
| A | TYR1414 |
| A | TRP1436 |
| A | CYS1438 |
| A | PRO1440 |
| A | TYR1446 |
| A | LYS1456 |
| A | ILE1457 |
| A | PRO1458 |
| A | ARG1462 |
| A | TRP1466 |
| A | PHE1467 |
| A | HOH2003 |
| B | LYS1407 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1 |
| Chain | Residue |
| B | CYS1163 |
| B | CYS1164 |
| B | HIS1255 |
| B | CYS1258 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2 |
| Chain | Residue |
| B | CYS1247 |
| B | CYS1250 |
| B | CYS1272 |
| B | CYS1275 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 3 |
| Chain | Residue |
| B | CYS1177 |
| B | CYS1183 |
| B | CYS1201 |
| B | CYS1204 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 01K B 700 |
| Chain | Residue |
| B | SER1396 |
| B | TYR1397 |
| B | LEU1398 |
| B | ASP1399 |
| B | SER1400 |
| B | ARG1410 |
| B | THR1411 |
| B | TYR1414 |
| B | TRP1436 |
| B | CYS1438 |
| B | PRO1440 |
| B | TYR1446 |
| B | LYS1456 |
| B | ILE1457 |
| B | PRO1458 |
| B | ARG1462 |
| B | TRP1466 |
| B | PHE1467 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVkspMdlstIkrkldtgq..Yqepwqyvddiwl.MfnNAwlY |
| Chain | Residue | Details |
| A | SER1072-TYR1131 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 214 |
| Details | Domain: {"description":"Bromo","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with histone","evidences":[{"source":"PubMed","id":"18273021","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24819397","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"B2RWS6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17065153","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine; by autocatalysis","evidences":[{"source":"PubMed","id":"15004546","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
