Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0008131 | molecular_function | primary amine oxidase activity |
| A | 0009308 | biological_process | amine metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048038 | molecular_function | quinone binding |
| A | 0052595 | molecular_function | aliphatic amine oxidase activity |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0008131 | molecular_function | primary amine oxidase activity |
| B | 0009308 | biological_process | amine metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048038 | molecular_function | quinone binding |
| B | 0052595 | molecular_function | aliphatic amine oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU A 701 |
| Chain | Residue |
| A | HIS431 |
| A | HIS433 |
| A | HIS592 |
| A | HOH932 |
| A | HOH1041 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 702 |
| Chain | Residue |
| A | SER529 |
| A | ARG532 |
| A | SER562 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR A 703 |
| Chain | Residue |
| A | SER374 |
| A | HIS345 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR A 704 |
| Chain | Residue |
| A | ASP128 |
| A | HOH1271 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 705 |
| Chain | Residue |
| A | GLY34 |
| A | PRO35 |
| A | GLU36 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 706 |
| Chain | Residue |
| A | ASP440 |
| A | MET441 |
| A | ASP581 |
| A | ILE582 |
| A | HOH831 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K A 707 |
| Chain | Residue |
| A | VAL79 |
| A | THR80 |
| A | ALA93 |
| A | ALA94 |
| A | SER562 |
| A | HOH898 |
| A | HOH1032 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 708 |
| Chain | Residue |
| A | ARG532 |
| A | ARG533 |
| A | THR554 |
| A | PHE557 |
| A | HIS561 |
| A | SER562 |
| A | GLY563 |
| A | GLY564 |
| A | ALA565 |
| A | HOH841 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 709 |
| Chain | Residue |
| A | GLU347 |
| A | ARG370 |
| A | GOL712 |
| A | HOH852 |
| A | HOH1196 |
| A | HOH1405 |
| A | HOH1442 |
| B | HOH1189 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 710 |
| Chain | Residue |
| A | ASP393 |
| A | GLU397 |
| A | LYS610 |
| A | HOH1207 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 711 |
| Chain | Residue |
| A | VAL159 |
| A | ASP161 |
| A | VAL197 |
| A | ALA199 |
| A | HOH1139 |
| A | HOH1172 |
| A | HOH1271 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 712 |
| Chain | Residue |
| A | ARG370 |
| A | GLU397 |
| A | GLU399 |
| A | GOL709 |
| A | HOH1293 |
| B | GOL711 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 713 |
| Chain | Residue |
| A | LEU590 |
| A | ASP605 |
| A | HOH1233 |
| A | HOH1290 |
| A | HOH1309 |
| B | HIS515 |
| B | LYS610 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 714 |
| Chain | Residue |
| A | LYS610 |
| A | ARG612 |
| A | HOH1217 |
| B | LEU590 |
| B | ASP605 |
| B | HOH1166 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU B 701 |
| Chain | Residue |
| B | HIS431 |
| B | HIS433 |
| B | HIS592 |
| B | HOH859 |
| B | HOH1042 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR B 702 |
| Chain | Residue |
| B | SER529 |
| B | ARG532 |
| B | GLY563 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 703 |
| Chain | Residue |
| B | HIS345 |
| B | SER374 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR B 704 |
| Chain | Residue |
| B | GLY34 |
| B | PRO35 |
| B | GLU36 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 705 |
| Chain | Residue |
| B | ASP128 |
| B | HOH1298 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 706 |
| Chain | Residue |
| B | ASP440 |
| B | MET441 |
| B | ASP581 |
| B | ILE582 |
| B | HOH854 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 707 |
| Chain | Residue |
| B | SER562 |
| B | HOH1099 |
| B | VAL79 |
| B | THR80 |
| B | ALA93 |
| B | ALA94 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 708 |
| Chain | Residue |
| B | ASN368 |
| B | ASP393 |
| B | HOH902 |
| B | HOH1024 |
| B | HOH1074 |
| B | HOH1113 |
| site_id | CC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 709 |
| Chain | Residue |
| B | VAL44 |
| B | LEU45 |
| B | ASP46 |
| B | ARG274 |
| B | ARG551 |
| B | TYR552 |
| B | HOH938 |
| B | HOH974 |
| B | HOH1308 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 710 |
| Chain | Residue |
| A | HOH1244 |
| B | GLU347 |
| B | ARG370 |
| B | GOL711 |
| B | HOH837 |
| B | HOH1003 |
| B | HOH1295 |
| B | HOH1310 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 711 |
| Chain | Residue |
| A | GOL712 |
| B | ARG370 |
| B | TYR389 |
| B | GLU397 |
| B | GLU399 |
| B | GOL710 |
| B | HOH1181 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 712 |
| Chain | Residue |
| A | ASP417 |
| B | SER471 |
| B | ARG472 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 713 |
| Chain | Residue |
| A | HIS517 |
| A | HOH1233 |
| B | HIS517 |
| B | HOH1134 |
Functional Information from PROSITE/UniProt
| site_id | PS01164 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY |
| Chain | Residue | Details |
| A | MET371-TYR384 | |
| site_id | PS01165 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP |
| Chain | Residue | Details |
| A | THR587-PRO600 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP298 | |
| B | ASP298 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807 |
| Chain | Residue | Details |
| A | TPQ382 | |
| B | TPQ382 | |
| Chain | Residue | Details |
| A | TYR296 | |
| B | TYR296 | |
| Chain | Residue | Details |
| A | ILE379 | |
| B | ILE379 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9405045, ECO:0007744|PDB:1AV4, ECO:0007744|PDB:1AVL, ECO:0007744|PDB:1IU7, ECO:0007744|PDB:1IVU, ECO:0007744|PDB:1IVV, ECO:0007744|PDB:1IVW, ECO:0007744|PDB:1IVX, ECO:0007744|PDB:1RJO, ECO:0007744|PDB:1SIH, ECO:0007744|PDB:1SII, ECO:0007744|PDB:1UI8, ECO:0007744|PDB:1W4N, ECO:0007744|PDB:1W5Z, ECO:0007744|PDB:1W6C, ECO:0007744|PDB:1W6G, ECO:0007744|PDB:2BT3, ECO:0007744|PDB:2CFD, ECO:0007744|PDB:2CFG, ECO:0007744|PDB:2CFK, ECO:0007744|PDB:2CFL, ECO:0007744|PDB:2CFW, ECO:0007744|PDB:2CG0, ECO:0007744|PDB:2CG1, ECO:0007744|PDB:2CWT, ECO:0007744|PDB:2CWU, ECO:0007744|PDB:2CWV, ECO:0007744|PDB:2D1W, ECO:0007744|PDB:2E2T, ECO:0007744|PDB:2E2U, ECO:0007744|PDB:2E2V, ECO:0007744|PDB:2YX9, ECO:0007744|PDB:2ZL8, ECO:0007744|PDB:3AMO, ECO:0007744|PDB:3KII, ECO:0007744|PDB:3KN4, ECO:0007744|PDB:3WA2, ECO:0007744|PDB:3WA3 |
| Chain | Residue | Details |
| A | HIS431 | |
| A | HIS433 | |
| A | HIS592 | |
| B | HIS431 | |
| B | HIS433 | |
| B | HIS592 | |
| Chain | Residue | Details |
| A | TPQ382 | |
| B | TPQ382 | |
