Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3X42

Crystal structure of copper amine oxidase from Arthrobacter globiformis in the presence of sodium bromide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0008131	molecular_function	primary methylamine oxidase activity
A	0009308	biological_process	amine metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
A	0046872	molecular_function	metal ion binding
A	0048038	molecular_function	quinone binding
B	0005507	molecular_function	copper ion binding
B	0008131	molecular_function	primary methylamine oxidase activity
B	0009308	biological_process	amine metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU A 701

Chain	Residue
A	HIS431
A	HIS433
A	HIS592
A	HOH932
A	HOH1041

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 702

Chain	Residue
A	SER529
A	ARG532
A	SER562

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 703

Chain	Residue
A	SER374
A	HIS345

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR A 704

Chain	Residue
A	ASP128
A	HOH1271

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 705

Chain	Residue
A	GLY34
A	PRO35
A	GLU36

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 706

Chain	Residue
A	ASP440
A	MET441
A	ASP581
A	ILE582
A	HOH831

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE K A 707

Chain	Residue
A	VAL79
A	THR80
A	ALA93
A	ALA94
A	SER562
A	HOH898
A	HOH1032

site_id	AC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 708

Chain	Residue
A	ARG532
A	ARG533
A	THR554
A	PHE557
A	HIS561
A	SER562
A	GLY563
A	GLY564
A	ALA565
A	HOH841

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 709

Chain	Residue
A	GLU347
A	ARG370
A	GOL712
A	HOH852
A	HOH1196
A	HOH1405
A	HOH1442
B	HOH1189

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 710

Chain	Residue
A	ASP393
A	GLU397
A	LYS610
A	HOH1207

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 711

Chain	Residue
A	VAL159
A	ASP161
A	VAL197
A	ALA199
A	HOH1139
A	HOH1172
A	HOH1271

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 712

Chain	Residue
A	ARG370
A	GLU397
A	GLU399
A	GOL709
A	HOH1293
B	GOL711

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 713

Chain	Residue
A	LEU590
A	ASP605
A	HOH1233
A	HOH1290
A	HOH1309
B	HIS515
B	LYS610

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 714

Chain	Residue
A	LYS610
A	ARG612
A	HOH1217
B	LEU590
B	ASP605
B	HOH1166

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU B 701

Chain	Residue
B	HIS431
B	HIS433
B	HIS592
B	HOH859
B	HOH1042

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 702

Chain	Residue
B	SER529
B	ARG532
B	GLY563

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR B 703

Chain	Residue
B	HIS345
B	SER374

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 704

Chain	Residue
B	GLY34
B	PRO35
B	GLU36

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR B 705

Chain	Residue
B	ASP128
B	HOH1298

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA B 706

Chain	Residue
B	ASP440
B	MET441
B	ASP581
B	ILE582
B	HOH854

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K B 707

Chain	Residue
B	SER562
B	HOH1099
B	VAL79
B	THR80
B	ALA93
B	ALA94

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 708

Chain	Residue
B	ASN368
B	ASP393
B	HOH902
B	HOH1024
B	HOH1074
B	HOH1113

site_id	CC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL B 709

Chain	Residue
B	VAL44
B	LEU45
B	ASP46
B	ARG274
B	ARG551
B	TYR552
B	HOH938
B	HOH974
B	HOH1308

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B 710

Chain	Residue
A	HOH1244
B	GLU347
B	ARG370
B	GOL711
B	HOH837
B	HOH1003
B	HOH1295
B	HOH1310

site_id	CC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 711

Chain	Residue
A	GOL712
B	ARG370
B	TYR389
B	GLU397
B	GLU399
B	GOL710
B	HOH1181

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL B 712

Chain	Residue
A	ASP417
B	SER471
B	ARG472

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 713

Chain	Residue
A	HIS517
A	HOH1233
B	HIS517
B	HOH1134

Functional Information from PROSITE/UniProt

site_id	PS01164
Number of Residues	14
Details	COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY

Chain	Residue	Details
A	MET371-TYR384

site_id	PS01165
Number of Residues	14
Details	COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP

Chain	Residue	Details
A	THR587-PRO600

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Schiff-base intermediate with substrate; via topaquinone","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AV4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IU7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RJO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W4N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BT3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2D1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZL8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KN4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"2',4',5'-topaquinone","evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)