1SII
AGAO in covalent complex with the inhibitor NOBA ("4-(2-naphthyloxy)-2-butyn-1-amine")
Summary for 1SII
Entry DOI | 10.2210/pdb1sii/pdb |
Related | 1AV4 1SIH |
Descriptor | Phenylethylamine oxidase, COPPER (II) ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | cao, cuao, copper-containing, amine oxidase, tpq, quinone, trihydroxyphenylalanine quinone, noba, 4-(2-naphthyloxy)-2-butyn-1-amine, 4-(aryloxy)-2-butynamine, suicide inhibition, oxidoreductase |
Biological source | Arthrobacter globiformis |
Total number of polymer chains | 1 |
Total formula weight | 72341.82 |
Authors | Guss, J.M.,Langley, D.B.,Duff, A.P. (deposition date: 2004-02-29, release date: 2004-09-07, Last modification date: 2017-10-11) |
Primary citation | O'Connell, K.M.,Langley, D.B.,Shepard, E.M.,Duff, A.P.,Jeon, H.B.,Sun, G.,Freeman, H.C.,Guss, J.M.,Sayre, L.M.,Dooley, D.M. Differential Inhibition of Six Copper Amine Oxidases by a Family of 4-(Aryloxy)-2-butynamines: Evidence for a New Mode of Inactivation. Biochemistry, 43:10965-10978, 2004 Cited by PubMed: 15323556DOI: 10.1021/bi0492004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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