Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3X3Z

Copper amine oxidase from Arthrobacter globiformis: Aminoresorcinol form produced by anaerobic reduction with ethylamine hydrochloride

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0008131	molecular_function	primary methylamine oxidase activity
A	0009308	biological_process	amine metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
A	0046872	molecular_function	metal ion binding
A	0048038	molecular_function	quinone binding
B	0005507	molecular_function	copper ion binding
B	0008131	molecular_function	primary methylamine oxidase activity
B	0009308	biological_process	amine metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016641	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU A 1001

Chain	Residue
A	HIS431
A	HIS433
A	HIS592
A	CL1002
A	HOH1342

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL A 1002

Chain	Residue
A	MET602
A	CU1001
A	HOH1110
A	TYQ382
A	HIS431
A	HIS433
A	HIS592

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 1003

Chain	Residue
A	ASP440
A	MET441
A	ASP581
A	ILE582
A	HOH1146

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE K A 1004

Chain	Residue
A	VAL79
A	THR80
A	ALA93
A	ALA94
A	ARG148
A	SER562
A	HOH1425
A	HOH1588

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 1005

Chain	Residue
A	THR521
A	LEU522
A	LEU523
A	THR538
A	HOH1122
A	HOH1725
B	ARG457
B	ARG490

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1006

Chain	Residue
A	ASP605
A	HOH1536
A	HOH1610
B	LYS610

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 1007

Chain	Residue
A	GLU347
A	ARG370
A	LYS401
A	GOL1010
A	HOH1155
A	HOH1242
A	HOH1430
B	TRP349
B	HOH1395

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1008

Chain	Residue
A	ASN368
A	ASP393
A	GLU397
A	HOH1289
A	HOH1317
A	HOH1428
A	HOH1582

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 1009

Chain	Residue
A	ILE39
A	TYR41
A	LEU42
A	SER329
A	ASP330
A	ALA331
A	HOH1496
A	HOH1730

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1010

Chain	Residue
A	ARG370
A	TYR389
A	GLU397
A	GLU399
A	GOL1007
A	HOH1764

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CU B 1001

Chain	Residue
B	TYQ382
B	HIS431
B	HIS433
B	HIS592
B	CL1002
B	HOH1888

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL B 1002

Chain	Residue
B	TYQ382
B	HIS431
B	HIS433
B	HIS592
B	CU1001
B	HOH1132
B	HOH1888

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 1003

Chain	Residue
B	ASP440
B	MET441
B	PHE446
B	ASP581
B	ILE582
B	HOH1119

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE K B 1004

Chain	Residue
B	VAL79
B	THR80
B	ALA93
B	ALA94
B	SER562
B	HOH1196
B	HOH1298

site_id	BC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL B 1005

Chain	Residue
B	GLY563
B	GLY564
B	ALA565
B	HOH1117
B	ARG532
B	ARG533
B	THR554
B	PHE557
B	HIS561
B	SER562

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 1006

Chain	Residue
A	ARG457
A	HOH1229
A	HOH1503
B	THR521
B	LEU522
B	THR538
B	HOH1120

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 1007

Chain	Residue
A	HOH1242
B	GLU347
B	ARG370
B	LYS401
B	HOH1202
B	HOH1372
B	HOH1895

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B 1008

Chain	Residue
A	TRP168
A	GLY380
B	ASP357
B	LEU358
B	TRP359
B	HOH1259
B	HOH1676
B	HOH1900

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL B 1009

Chain	Residue
A	LYS610
A	ARG612
B	ASP605
B	THR606
B	HOH1479

site_id	CC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 1010

Chain	Residue
B	ASP161
B	VAL197
B	PRO198
B	ALA199
B	HOH1388
B	HOH1641
B	HOH1661

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 1011

Chain	Residue
A	HOH1133
A	HOH1183
B	PRO136
B	TRP168
B	GLY380
B	HOH1622
B	HOH1781

Functional Information from PROSITE/UniProt

site_id	PS01164
Number of Residues	14
Details	COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY

Chain	Residue	Details
A	MET371-TYR384

site_id	PS01165
Number of Residues	14
Details	COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP

Chain	Residue	Details
A	THR587-PRO600

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Schiff-base intermediate with substrate; via topaquinone","evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1AV4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IU7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IVX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RJO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SIH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1SII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W4N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BT3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2D1W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E2V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2YX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZL8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KN4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3WA3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"2',4',5'-topaquinone","evidences":[{"source":"PubMed","id":"9405045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)