Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0008131 | molecular_function | primary amine oxidase activity |
| A | 0009308 | biological_process | amine metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048038 | molecular_function | quinone binding |
| A | 0052595 | molecular_function | aliphatic amine oxidase activity |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0008131 | molecular_function | primary amine oxidase activity |
| B | 0009308 | biological_process | amine metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048038 | molecular_function | quinone binding |
| B | 0052595 | molecular_function | aliphatic amine oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU A 1001 |
| Chain | Residue |
| A | HIS431 |
| A | HIS433 |
| A | HIS592 |
| A | CL1002 |
| A | HOH1342 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL A 1002 |
| Chain | Residue |
| A | MET602 |
| A | CU1001 |
| A | HOH1110 |
| A | TYQ382 |
| A | HIS431 |
| A | HIS433 |
| A | HIS592 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1003 |
| Chain | Residue |
| A | ASP440 |
| A | MET441 |
| A | ASP581 |
| A | ILE582 |
| A | HOH1146 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE K A 1004 |
| Chain | Residue |
| A | VAL79 |
| A | THR80 |
| A | ALA93 |
| A | ALA94 |
| A | ARG148 |
| A | SER562 |
| A | HOH1425 |
| A | HOH1588 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1005 |
| Chain | Residue |
| A | THR521 |
| A | LEU522 |
| A | LEU523 |
| A | THR538 |
| A | HOH1122 |
| A | HOH1725 |
| B | ARG457 |
| B | ARG490 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1006 |
| Chain | Residue |
| A | ASP605 |
| A | HOH1536 |
| A | HOH1610 |
| B | LYS610 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1007 |
| Chain | Residue |
| A | GLU347 |
| A | ARG370 |
| A | LYS401 |
| A | GOL1010 |
| A | HOH1155 |
| A | HOH1242 |
| A | HOH1430 |
| B | TRP349 |
| B | HOH1395 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1008 |
| Chain | Residue |
| A | ASN368 |
| A | ASP393 |
| A | GLU397 |
| A | HOH1289 |
| A | HOH1317 |
| A | HOH1428 |
| A | HOH1582 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1009 |
| Chain | Residue |
| A | ILE39 |
| A | TYR41 |
| A | LEU42 |
| A | SER329 |
| A | ASP330 |
| A | ALA331 |
| A | HOH1496 |
| A | HOH1730 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1010 |
| Chain | Residue |
| A | ARG370 |
| A | TYR389 |
| A | GLU397 |
| A | GLU399 |
| A | GOL1007 |
| A | HOH1764 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CU B 1001 |
| Chain | Residue |
| B | TYQ382 |
| B | HIS431 |
| B | HIS433 |
| B | HIS592 |
| B | CL1002 |
| B | HOH1888 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 1002 |
| Chain | Residue |
| B | TYQ382 |
| B | HIS431 |
| B | HIS433 |
| B | HIS592 |
| B | CU1001 |
| B | HOH1132 |
| B | HOH1888 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 1003 |
| Chain | Residue |
| B | ASP440 |
| B | MET441 |
| B | PHE446 |
| B | ASP581 |
| B | ILE582 |
| B | HOH1119 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K B 1004 |
| Chain | Residue |
| B | VAL79 |
| B | THR80 |
| B | ALA93 |
| B | ALA94 |
| B | SER562 |
| B | HOH1196 |
| B | HOH1298 |
| site_id | BC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 1005 |
| Chain | Residue |
| B | GLY563 |
| B | GLY564 |
| B | ALA565 |
| B | HOH1117 |
| B | ARG532 |
| B | ARG533 |
| B | THR554 |
| B | PHE557 |
| B | HIS561 |
| B | SER562 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1006 |
| Chain | Residue |
| A | ARG457 |
| A | HOH1229 |
| A | HOH1503 |
| B | THR521 |
| B | LEU522 |
| B | THR538 |
| B | HOH1120 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1007 |
| Chain | Residue |
| A | HOH1242 |
| B | GLU347 |
| B | ARG370 |
| B | LYS401 |
| B | HOH1202 |
| B | HOH1372 |
| B | HOH1895 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1008 |
| Chain | Residue |
| A | TRP168 |
| A | GLY380 |
| B | ASP357 |
| B | LEU358 |
| B | TRP359 |
| B | HOH1259 |
| B | HOH1676 |
| B | HOH1900 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1009 |
| Chain | Residue |
| A | LYS610 |
| A | ARG612 |
| B | ASP605 |
| B | THR606 |
| B | HOH1479 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1010 |
| Chain | Residue |
| B | ASP161 |
| B | VAL197 |
| B | PRO198 |
| B | ALA199 |
| B | HOH1388 |
| B | HOH1641 |
| B | HOH1661 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1011 |
| Chain | Residue |
| A | HOH1133 |
| A | HOH1183 |
| B | PRO136 |
| B | TRP168 |
| B | GLY380 |
| B | HOH1622 |
| B | HOH1781 |
Functional Information from PROSITE/UniProt
| site_id | PS01164 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY |
| Chain | Residue | Details |
| A | MET371-TYR384 | |
| site_id | PS01165 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP |
| Chain | Residue | Details |
| A | THR587-PRO600 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP298 | |
| B | ASP298 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807 |
| Chain | Residue | Details |
| A | TYQ382 | |
| B | TYQ382 | |
| Chain | Residue | Details |
| A | TYR296 | |
| B | TYR296 | |
| Chain | Residue | Details |
| A | ILE379 | |
| B | ILE379 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9405045, ECO:0007744|PDB:1AV4, ECO:0007744|PDB:1AVL, ECO:0007744|PDB:1IU7, ECO:0007744|PDB:1IVU, ECO:0007744|PDB:1IVV, ECO:0007744|PDB:1IVW, ECO:0007744|PDB:1IVX, ECO:0007744|PDB:1RJO, ECO:0007744|PDB:1SIH, ECO:0007744|PDB:1SII, ECO:0007744|PDB:1UI8, ECO:0007744|PDB:1W4N, ECO:0007744|PDB:1W5Z, ECO:0007744|PDB:1W6C, ECO:0007744|PDB:1W6G, ECO:0007744|PDB:2BT3, ECO:0007744|PDB:2CFD, ECO:0007744|PDB:2CFG, ECO:0007744|PDB:2CFK, ECO:0007744|PDB:2CFL, ECO:0007744|PDB:2CFW, ECO:0007744|PDB:2CG0, ECO:0007744|PDB:2CG1, ECO:0007744|PDB:2CWT, ECO:0007744|PDB:2CWU, ECO:0007744|PDB:2CWV, ECO:0007744|PDB:2D1W, ECO:0007744|PDB:2E2T, ECO:0007744|PDB:2E2U, ECO:0007744|PDB:2E2V, ECO:0007744|PDB:2YX9, ECO:0007744|PDB:2ZL8, ECO:0007744|PDB:3AMO, ECO:0007744|PDB:3KII, ECO:0007744|PDB:3KN4, ECO:0007744|PDB:3WA2, ECO:0007744|PDB:3WA3 |
| Chain | Residue | Details |
| A | HIS431 | |
| A | HIS433 | |
| A | HIS592 | |
| B | HIS431 | |
| B | HIS433 | |
| B | HIS592 | |
| Chain | Residue | Details |
| A | TYQ382 | |
| B | TYQ382 | |
