3Q24
X-ray crystal structure of the N4 mini-VRNAP and P2_7a promoter transcription initiation complex with pppGpG and pyrophosphate: product complex
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GTP A 1106 |
| Chain | Residue |
| A | ARG424 |
| A | HOH2160 |
| A | HOH2161 |
| A | HOH2211 |
| A | HOH2245 |
| C | DC5 |
| C | DA6 |
| A | LYS437 |
| A | ARG440 |
| A | ILE949 |
| A | ASP951 |
| A | 5GP1107 |
| A | HOH1545 |
| A | HOH1608 |
| A | HOH2158 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 5GP A 1107 |
| Chain | Residue |
| A | ARG424 |
| A | GLY564 |
| A | PRO565 |
| A | ASN671 |
| A | THR674 |
| A | TYR678 |
| A | ASP951 |
| A | GTP1106 |
| A | HOH1273 |
| A | HOH1432 |
| A | HOH2161 |
| C | DC4 |
| C | DC5 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2HP A 1108 |
| Chain | Residue |
| A | GLN469 |
| A | ILE473 |
| A | LYS474 |
| A | VAL475 |
| A | HIS476 |
| A | HOH1204 |
| A | HOH1250 |
| A | HOH1618 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE POP A 1109 |
| Chain | Residue |
| A | GLY560 |
| A | VAL561 |
| A | THR562 |
| A | TYR612 |
| A | ARG666 |
| A | LYS670 |
| A | HOH1284 |
| A | HOH1612 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2HP B 1106 |
| Chain | Residue |
| B | GLN469 |
| B | ILE473 |
| B | LYS474 |
| B | VAL475 |
| B | HIS476 |
| B | HOH1876 |
| B | HOH1950 |
| B | HOH2646 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE POP B 1107 |
| Chain | Residue |
| B | HIS476 |
| B | GLY560 |
| B | VAL561 |
| B | THR562 |
| B | ASP610 |
| B | TYR612 |
| B | ARG666 |
| B | HOH1888 |
| B | HOH2130 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21321236","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23235152","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
