3LLU
Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005525 | molecular_function | GTP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE GNP A 501 |
| Chain | Residue |
| A | HOH27 |
| A | SER75 |
| A | SER76 |
| A | THR90 |
| A | LEU91 |
| A | SER95 |
| A | THR96 |
| A | GLY119 |
| A | GLN147 |
| A | HIS178 |
| A | LYS179 |
| A | HOH28 |
| A | ASP181 |
| A | SER219 |
| A | ILE220 |
| A | HOH243 |
| A | HOH247 |
| A | HOH258 |
| A | HOH285 |
| A | MG502 |
| A | HOH38 |
| A | HOH41 |
| A | ARG70 |
| A | ARG71 |
| A | SER72 |
| A | GLY73 |
| A | LYS74 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | HOH41 |
| A | SER75 |
| A | THR96 |
| A | HOH243 |
| A | GNP501 |
Functional Information from PROSITE/UniProt
| site_id | PS00214 |
| Number of Residues | 18 |
| Details | FABP Cytosolic fatty-acid binding proteins signature. KAYkVnpDmNFEvFIHKV |
| Chain | Residue | Details |
| A | LYS163-VAL180 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601708, ECO:0000269|PubMed:31601764, ECO:0000269|PubMed:35338845, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6SB0, ECO:0007744|PDB:6SB2, ECO:0007744|PDB:6U62, ECO:0007744|PDB:7T3C, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | ARG71 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601764, ECO:0000269|PubMed:35338845, ECO:0007744|PDB:6SB0, ECO:0007744|PDB:6SB2, ECO:0007744|PDB:7T3B, ECO:0007744|PDB:7T3C |
| Chain | Residue | Details |
| A | SER72 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601708, ECO:0000269|PubMed:31601764, ECO:0000269|PubMed:35338845, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6SB0, ECO:0007744|PDB:6U62, ECO:0007744|PDB:7T3B, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | GLY73 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32868926, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6WJ2, ECO:0007744|PDB:6WJ3, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | LYS74 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601708, ECO:0000269|PubMed:31601764, ECO:0000269|PubMed:32868926, ECO:0000269|PubMed:35338845, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6SB0, ECO:0007744|PDB:6SB2, ECO:0007744|PDB:6U62, ECO:0007744|PDB:6WJ2, ECO:0007744|PDB:6WJ3, ECO:0007744|PDB:7T3B, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | SER75 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601764, ECO:0000269|PubMed:35338845, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6SB0, ECO:0007744|PDB:6SB2, ECO:0007744|PDB:7T3C, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | SER76 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32868926, ECO:0007744|PDB:6WJ2, ECO:0007744|PDB:6WJ3 |
| Chain | Residue | Details |
| A | THR90 | |
| A | THR96 | |
| A | ASP181 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:35338845, ECO:0007744|PDB:7T3B, ECO:0007744|PDB:7T3C |
| Chain | Residue | Details |
| A | GLU94 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601708, ECO:0000269|PubMed:32868926, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6U62, ECO:0007744|PDB:6WJ2, ECO:0007744|PDB:6WJ3, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | HIS178 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31601708, ECO:0000269|PubMed:35338845, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:6U62, ECO:0007744|PDB:7T3B, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | LYS179 | |
| A | ILE220 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:35338845, ECO:0000269|PubMed:36697823, ECO:0007744|PDB:7T3B, ECO:0007744|PDB:7UX2, ECO:0007744|PDB:7UXC, ECO:0007744|PDB:7UXH |
| Chain | Residue | Details |
| A | SER219 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q99K70 |
| Chain | Residue | Details |
| A | THR96 |
