6WJ2
CryoEM structure of the SLC38A9-RagA-RagC-Ragulator complex in the pre-GAP state
Summary for 6WJ2
Entry DOI | 10.2210/pdb6wj2/pdb |
Related | 6WJ3 |
EMDB information | 21686 21687 |
Descriptor | Ragulator complex protein LAMTOR1, 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, MAGNESIUM ION, ... (11 entities in total) |
Functional Keywords | small gtpase, mtorc1 activation, amino acid signaling, lysosome, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 173278.65 |
Authors | Fromm, S.A.,Hurley, J.H. (deposition date: 2020-04-11, release date: 2020-09-02, Last modification date: 2024-03-06) |
Primary citation | Fromm, S.A.,Lawrence, R.E.,Hurley, J.H. Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. Nat.Struct.Mol.Biol., 27:1017-1023, 2020 Cited by PubMed: 32868926DOI: 10.1038/s41594-020-0490-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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