7T3B

GATOR1-RAG-RAGULATOR - GAP Complex

Summary for 7T3B

• Entry DOI: 10.2210/pdb7t3b/pdb
• EMDB information: 25653
• Descriptor: Ras-related GTP-binding protein C, Ras-related GTP-binding protein A, GUANOSINE-5'-DIPHOSPHATE, ... (12 entities in total)
• Functional Keywords: complex, gtpase activating protein, nutrient sensing, metabolism, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 435937.42

Authors

Egri, S.B.,Shen, K. (deposition date: 2021-12-07, release date: 2022-04-06, Last modification date: 2022-06-01)

• Primary citation: Egri, S.B.,Ouch, C.,Chou, H.T.,Yu, Z.,Song, K.,Xu, C.,Shen, K.; Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.; Mol.Cell, 82:1836-, 2022; PubMed: 35338845; DOI: 10.1016/j.molcel.2022.03.002

Experimental method

ELECTRON MICROSCOPY (3.9 Å)