3K23
Glucocorticoid Receptor with Bound D-prolinamide 11
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE JZN A 1 |
| Chain | Residue |
| A | GLU540 |
| A | MET604 |
| A | ALA605 |
| A | ALA607 |
| A | LEU608 |
| A | ARG611 |
| A | PHE623 |
| A | CYS736 |
| A | LEU753 |
| A | PRO541 |
| A | MET560 |
| A | LEU563 |
| A | ASN564 |
| A | LEU566 |
| A | GLN570 |
| A | MET601 |
| A | LEU603 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE JZN B 2 |
| Chain | Residue |
| B | GLU540 |
| B | MET560 |
| B | LEU563 |
| B | ASN564 |
| B | LEU566 |
| B | GLN570 |
| B | MET601 |
| B | MET604 |
| B | ALA607 |
| B | ARG611 |
| B | PHE623 |
| B | GLN642 |
| B | MET646 |
| B | LYS667 |
| B | LEU732 |
| B | TYR735 |
| B | LEU753 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE JZN C 3 |
| Chain | Residue |
| C | GLU540 |
| C | MET560 |
| C | LEU563 |
| C | ASN564 |
| C | LEU566 |
| C | GLY567 |
| C | GLN570 |
| C | LEU603 |
| C | MET604 |
| C | ALA605 |
| C | ALA607 |
| C | LEU608 |
| C | ARG611 |
| C | PHE623 |
| C | MET646 |
| C | LEU732 |
| C | CYS736 |
| C | LEU753 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"12144530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 165 |
| Details | Region: {"description":"Interaction with CRY1","evidences":[{"source":"PubMed","id":"22170608","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Motif: {"description":"LXXLL motif 3"} |
| Chain | Residue | Details |
