2X1W
Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008083 | molecular_function | growth factor activity |
| A | 0016020 | cellular_component | membrane |
| B | 0008083 | molecular_function | growth factor activity |
| B | 0016020 | cellular_component | membrane |
| C | 0008083 | molecular_function | growth factor activity |
| C | 0016020 | cellular_component | membrane |
| D | 0008083 | molecular_function | growth factor activity |
| D | 0016020 | cellular_component | membrane |
| L | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| L | 0005524 | molecular_function | ATP binding |
| L | 0006468 | biological_process | protein phosphorylation |
| L | 0016020 | cellular_component | membrane |
| L | 0019838 | molecular_function | growth factor binding |
| L | 0048010 | biological_process | vascular endothelial growth factor receptor signaling pathway |
| M | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| M | 0005524 | molecular_function | ATP binding |
| M | 0006468 | biological_process | protein phosphorylation |
| M | 0016020 | cellular_component | membrane |
| M | 0019838 | molecular_function | growth factor binding |
| M | 0048010 | biological_process | vascular endothelial growth factor receptor signaling pathway |
| N | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| N | 0005524 | molecular_function | ATP binding |
| N | 0006468 | biological_process | protein phosphorylation |
| N | 0016020 | cellular_component | membrane |
| N | 0019838 | molecular_function | growth factor binding |
| N | 0048010 | biological_process | vascular endothelial growth factor receptor signaling pathway |
| O | 0005021 | molecular_function | vascular endothelial growth factor receptor activity |
| O | 0005524 | molecular_function | ATP binding |
| O | 0006468 | biological_process | protein phosphorylation |
| O | 0016020 | cellular_component | membrane |
| O | 0019838 | molecular_function | growth factor binding |
| O | 0048010 | biological_process | vascular endothelial growth factor receptor signaling pathway |
Functional Information from PROSITE/UniProt
| site_id | PS00249 |
| Number of Residues | 13 |
| Details | PDGF_1 Platelet-derived growth factor (PDGF) family signature. PPCVsvyRCGGCC |
| Chain | Residue | Details |
| A | PRO154-CYS166 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20145116","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23878260","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 96 |
| Details | Domain: {"description":"Ig-like C2-type 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20145116","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20145116","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21827946","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 132 |
| Details | Domain: {"description":"Ig-like C2-type 2"} |
| Chain | Residue | Details |
