2X1W

Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008083	molecular_function	growth factor activity
A	0016020	cellular_component	membrane
B	0008083	molecular_function	growth factor activity
B	0016020	cellular_component	membrane
C	0008083	molecular_function	growth factor activity
C	0016020	cellular_component	membrane
D	0008083	molecular_function	growth factor activity
D	0016020	cellular_component	membrane
L	0005021	molecular_function	vascular endothelial growth factor receptor activity
L	0005524	molecular_function	ATP binding
L	0006468	biological_process	protein phosphorylation
L	0016020	cellular_component	membrane
L	0019838	molecular_function	growth factor binding
L	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway
M	0005021	molecular_function	vascular endothelial growth factor receptor activity
M	0005524	molecular_function	ATP binding
M	0006468	biological_process	protein phosphorylation
M	0016020	cellular_component	membrane
M	0019838	molecular_function	growth factor binding
M	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway
N	0005021	molecular_function	vascular endothelial growth factor receptor activity
N	0005524	molecular_function	ATP binding
N	0006468	biological_process	protein phosphorylation
N	0016020	cellular_component	membrane
N	0019838	molecular_function	growth factor binding
N	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway
O	0005021	molecular_function	vascular endothelial growth factor receptor activity
O	0005524	molecular_function	ATP binding
O	0006468	biological_process	protein phosphorylation
O	0016020	cellular_component	membrane
O	0019838	molecular_function	growth factor binding
O	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00249
Number of Residues	13
Details	PDGF_1 Platelet-derived growth factor (PDGF) family signature. PPCVsvyRCGGCC

Chain	Residue	Details
A	PRO154-CYS166

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20145116

Chain	Residue	Details
L	ASN143
M	ASN143
N	ASN143
O	ASN143
C	ASN175
C	ASN205
D	ASN175
D	ASN205

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
L	ASN158
M	ASN158
N	ASN158
O	ASN158

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site_id	SWS_FT_FI3
Number of Residues	8
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20145116, ECO:0000269|PubMed:21827946

Chain	Residue	Details
L	ASN245
L	ASN318
M	ASN245
M	ASN318
N	ASN245
N	ASN318
O	ASN245
O	ASN318

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