1XDD
X-ray structure of LFA-1 I-domain in complex with LFA703 at 2.2A resolution
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 312 |
| Chain | Residue |
| A | SER139 |
| A | SER141 |
| A | ASP239 |
| A | HOH403 |
| A | HOH405 |
| A | HOH408 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 312 |
| Chain | Residue |
| B | HOH502 |
| B | HOH503 |
| B | HOH505 |
| B | SER139 |
| B | SER141 |
| B | ASP239 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE AAY A 401 |
| Chain | Residue |
| A | GLY128 |
| A | VAL130 |
| A | LEU132 |
| A | TYR166 |
| A | THR231 |
| A | ILE235 |
| A | TYR257 |
| A | HOH421 |
| A | HOH433 |
| A | HOH476 |
| A | HOH487 |
| A | HOH507 |
| B | GLN303 |
| B | LYS304 |
| B | LYS305 |
| B | TYR307 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AAY B 501 |
| Chain | Residue |
| A | LYS304 |
| A | TYR307 |
| B | VAL130 |
| B | TYR166 |
| B | THR231 |
| B | ILE235 |
| B | TYR257 |
| B | GLU284 |
| B | GLU301 |
| B | HOH528 |
| B | HOH541 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 342 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
